Plants perform these regulations mainly by regulating nuclear gene expression and
multiple intracellular signaling pathways have been shown to play a role in the genomic response of plants to stress, but the processes are not well understood.
The accumulation of calcium can then regulate the contraction of muscles, trigger the release of neurotransmitters or hormones,
modulate intracellular signaling pathways, and impact several other calcium - dependent cellular functions.
Researchers have discovered that genetic mutations underlying two inherited eye disorders arise in different components of a
single intracellular signaling pathway that is responsible for development...
Several target molecules have also been identified in
intracellular signalling pathways and in cell survival proteins.
Important advances have included the discovery of the first evidence that the odour response is governed by neurons, of
the intracellular signalling pathways between odorant receptors and sensory neurons, and of specific neurons, receptors and neurotransmitters involved in behaviour adaption following experience.
With similar precision, Professor Bargmann has also identified many of
the intracellular signalling pathways in C. elegans that relay information from cell surface odorant receptors (G protein - coupled receptors) to the interior of each sensory neuron.
Here, Dr. Tam presents data characterizing
the intracellular signaling pathway associated with the RANK — RANKL axis, as well as the effect in dendritic cells, antigen - specific T cells, cytokines, and chemokine profiles after in vivo treatment with blocking PD - L1 and T cell - depleting antibodies in a melanoma cancer model.