Sentences with phrase «intracranial volume»
"Intracranial volume" refers to the amount of space inside the skull, specifically within the brain. Full definition
Scientists collaborating across 250 institutions in 35 countries have identified variations of the genetic code that are associated with intracranial volume, which is a reflection of the maximum brain volume an individual achieves over a lifetime.
nimh.nih.gov
When researchers measured intracranial volume in people in the PREDICT - HD observational trial, they discovered that it was related to a person's height and gender.
Compared to controls, patients with schizophrenia demonstrated smaller bilateral hippocampus, amygdala, thalamus and accumbens volumes as well as intracranial volume, but larger bilateral caudate, putamen, pallidum and lateral ventricle volumes.
«The ability to identify genetic variants that affect intracranial volume, cognitive function, and cell proliferation and growth may offer important clues to the cellular processes through which genetic risk for a disease is translated into abnormalities in the brain,» said Friedman - Hill.
Thompson says that the next step in this work is to look not just at intracranial volume but the brain's connections or its function using other brain imaging modalities such as diffusion tensor imaging or functional MRI.
Intracranial volume robustly correlated positively with age of onset of PTSD trauma (i.e., smaller brains were associated with earlier onset of trauma) and negatively with duration of abuse.
In contrast, right, left, and total lateral ventricles were proportionally larger than controls, after adjustment for intracranial volume.
Surprisingly, after this correction, the total intracranial volume was still about 4 % smaller in men carrying the HD mutation than men without it.
Building on this work, the team has now determined that there are seven areas in our DNA where differences in the genetic code are associated with intracranial volume, which is the size of the skull cavity in which the brain resides.
The study also showed that the genetic influences on intelligence are highly correlated with genetic influences on educational attainment, and also, albeit less strongly, with smoking cessation, intracranial volume, head circumference in infancy, autism spectrum disorder and height.
Since the brain shrinks as we age, intracranial volume is thought to represent the size of the brain at its largest point.
The researchers also suggested that genes related to intracranial volume may affect DNA replication, the growth of neural stem cells, and signaling in the brain.
«When the scientists zeroed in on the DNA of people whose images showed smaller brains, they found a consistent relationship between subtle shifts in the genetic code and their intracranial volume, risk for Parkinson's disease, and even cognitive ability,» said Thompson.
Data scientists discover seven genetic variants linked to intracranial volume, Parkinson's disease risk, and cognitive ability
Intracranial volume is an MRI measurement that reflects the largest size a brain ever achieves.
We call this the intracranial volume.
They examined the intracranial volume of people with and without the HD mutation enrolled in the PREDICT - HD study.
The relationship of birth weight to indicators of brain development, including regional cortical area and thickness, striatal volumes, TBV, and intracranial volume, were investigated, controlling for variations in age, sex, household income, and GAF as well as scanner used.
Symptoms of intrusive thoughts, avoidance, hyperarousal and dissociation correlated positively with ventricular volume, and negatively with intracranial volume and total corpus callosurn and regional measures.