BAZ2 - ICR showed very high solubility (25 mM in D2O), a measured log D of 1.05, high stability in mouse microsomes, and permeation in the CaCo - 2 model and thus a suitable profile for oral and
intravenous gavage.
Personnel have experience in
gavage, intraperitoneal injection,
intravenous injection, as well as implantation of Alzet mini-osmotic pumps, for long term drug interventions.