Sentences with phrase «introducing additional mutations»

However, scientists» ability to selectively modify DNA errors without introducing additional mutations into a patient's genome remains a challenge.

«We're going to introduce additional mutations to sensitize the virus even more to the innate immune response and prevent the infection from spreading,» said Diamond, who also is a professor of molecular microbiology, and of pathology and immunology.

Once the tumors are established in the mice, the researchers can introduce additional mutations at any time, allowing them to study the influence of each mutation on tumor initiation, progression, and metastasis.

Not exact matches

The authors conclude by raising what they consider to be «a broader ethical problem with OAR,» stating that this procedure amounts to nothing more than human cloning with the additional twist of introducing a genetic mutation» ominously concluding that a «combination of wrongs can not make the end result good.»

As an additional safety feature, the researchers introduced two mutations that weakened the virus's ability to combat the cell's defenses against infection, reasoning that the mutated virus still would be able to grow in tumor cells — which have a poor antiviral defense system — but would be eliminated quickly in healthy cells with a robust antiviral response.