Sentences with phrase «introduction of new environments»

Later, the introduction of new environments can be more confusing for your young dog.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Given the absence of a public trading market of our common stock, and in accordance with the American Institute of Certified Public Accountants Accounting and Valuation Guide, Valuation of Privately - Held Company Equity Securities Issued as Compensation, our board of directors exercised reasonable judgment and considered numerous and subjective factors to determine the best estimate of fair value of our common stock, including independent third - party valuations of our common stock; the prices at which we sold shares of our convertible preferred stock to outside investors in arms - length transactions; the rights, preferences, and privileges of our convertible preferred stock relative to those of our common stock; our operating results, financial position, and capital resources; current business conditions and projections; the lack of marketability of our common stock; the hiring of key personnel and the experience of our management; the introduction of new products; our stage of development and material risks related to our business; the fact that the option grants involve illiquid securities in a private company; the likelihood of achieving a liquidity event, such as an initial public offering or a sale of our company given the prevailing market conditions and the nature and history of our business; industry trends and competitive environment; trends in consumer spending, including consumer confidence; and overall economic indicators, including gross domestic product, employment, inflation and interest rates, and the general economic outlook.

Buyer Behavior: the behaviors exhibited by buyers are directly affected by the changes related to context such as their environments, current situation, frameworks, goals, and the introduction of new social technology.

NEW YORK, NY, October 9, 2017 — Despite widespread criticism regarding the heightened regulatory environment that has pervaded since the introduction of the Dodd - Frank Wall Street Reform and Consumer Protection Act, as well as the Trump administration's promises to scale back regulations, the alternative investment industry doesn't foresee any lessening of current regulations or regulators»...

Many mattress materials used today contain chemicals used to improve comfort, but Naturepedic believes the introduction of new chemicals into our sleep environments is too high a price to pay for comfort.

More recently, as part of its response to the Roberts Review, the Government has proposed the introduction of new Academic Fellowships that will offer a more stable environment in which researchers can build their expertise and reputation, providing career - related training and, importantly, a permanent position at the end of the 5 - year awards.

About 75 % of survey respondents reported having been offered some kind of introduction to their new working environment.

«It suggests that bees may be able to respond quickly to novel problems that arise in their environment,» such as the introduction of new flowering plants and the loss of familiar ones, says Daniel Papaj, an evolutionary biologist at the University of Arizona in Tucson.

Moving to the far future allows for the introduction of new mechanics, equipment, and especially environments that couldn't be done in other time periods.

This piece provides an introduction to yield and how the low - rate environment has led investors to search globally for new sources of income.

These stories illustrate the introductions of two different cats to their new homes, but here are some general tips for introducing a feline into a new environment / home:

Environmental changes such as introduction of a new household member or change in the physical environment

The risk of disease exposure in susceptible animals is high whenever there are frequent introductions of new animals with an unknown health status, so foster homes and home - based rescue groups also represent a relatively «high risk» environment if they provide care for susceptible animals from different sources.

Stress - the introduction of new pets and changes in your dogs environment, also extreme weather such as heat or cold

The introduction of new enemies and environment objects between stages and levels do help alleviate that repetitive feeling.

The environment design is faithful to the subject matter as it includes iconic environments from Star Wars films such as the remote desert planet of Jakku and the ice planet of Starkiller Base containing a deadly energy weapon within the core of the planet, while a new feature which generally sets environments apart from this game in comparison to other LEGO games is the introduction of multi-build paths that effectively allows players to build an object to complete a new objective or reach a new area, dismantle it, then re-build it as an alternative object in order to complete another new objective or reach another new area.

1962 Introductions 1936 - 1948, Willard Gallery, New York, NY Masters of American Watercolor, Whitney Museum of American Art, New York, NY The First 5 Years: Acquisitions by the Friends of the Whitney Museum of American Art 10th Annual Exhibition, Museum of Art of Ogunquit, Ogunquit, ME The Artist's Environment: The West Coast, Amon Carter Museum of Western Art, Fort Worth, TX American Art Since 1950, Institute of Contemporary Art, Boston, MA 7th Annual International Exhibition of Modern Art, Mary Washington College, Fredericksburg, VA

The Council of the American Physical Society believes that the use of renewable energy sources, the adoption of new ways of producing and using fossil fuels, increased consideration of safe and cost effective uses of nuclear power, and the introduction of energy - efficient technologies can, over time, promote the United States» energy security and reduce stress on the world's environment.

Entering a New World (pdf) Introduction A Massive Market Failure Environment and Civilization China: Why the Existing Economic Model Will Fail Mounting Stresses, Failing States A Civilizational Tipping Point Plan B — A Plan of Hope Chapter 1 Data (xls)

Co-head Peter Blackmore recently advised the Qatari Ministry of Municipality and Environment on drafting new urban planning legislation for the introduction of a reformed planning system as part of the Qatar National Master Plan.

Success - oriented Technology Professional acknowledged for cost - effective integration of Process and Materials with market specific Quality to enable New Product Introduction delivery on - time within a High Volume / High Mix Manufacturing environment.