The microscope has been used to peer inside blood vessels being
invaded by cancer cells and capture white blood cells while they chomp down on sugars inside a fish eyeball.
Not exact matches
Dr Claudia Wellbrock, study author and
Cancer Research UK scientist at The University of Manchester and a member of the Manchester Cancer Research Centre, said: «We used to think that cancer cells spread by first specialising in invading other parts of the body and then change in order to grow ra
Cancer Research UK scientist at The University of Manchester and a member of the Manchester
Cancer Research Centre, said: «We used to think that cancer cells spread by first specialising in invading other parts of the body and then change in order to grow ra
Cancer Research Centre, said: «We used to think that
cancer cells spread by first specialising in invading other parts of the body and then change in order to grow ra
cancer cells spread
by first specialising in
invading other parts of the body and then change in order to grow rapidly.
The
cancer cell does so
by forming short - lived invadopodia — foot - like protrusions these
cells use to
invade.
U of G scientists have made a discovery that could reduce the spread of
cancer by hindering a protein that binds
cancer cells together and allows them to
invade tissues.
The research suggests that reducing production of the protein, called myoferlin, affects
cancer cells in two primary ways:
by changing the activation of many genes involved in metastasis in favor of normal
cell behavior, and
by altering mechanical properties of
cancer cells — including their shape and ability to
invade — so they are more likely to remain nested together rather than breaking away to travel to other tissues.
For several years, the research team from the Turku Centre for Biotechnology lead
by Professor Johanna Ivaska has focused their efforts on understanding how
cancer cells move and
invade surrounding tissue.
They believe the mutated gene causes
cancer by triggering cytoskeleton malfunction, which allows the
cancer cells to move more quickly than normal
cells, essentially
invading the surrounding healthy tissue.
Normally, T -
cells protect us from infection
by patrolling the body, seeking out specific protein signatures that indicate
invading bacteria, viruses or
cancer cells, and then rallying more T -
cells together to attack the threat.
However, the exact cytoskeletal strategy that the
cell uses to cross the physical BM barrier depends on the physiological context and the physical environment, as observed
by examining actin structures in
invading cancer and immune
cells, and in
cells that
invade during developmental processes such as angiogenesis and anchor
cell invasion in Caenorhabditis elegans.
Molecular surgical tools, guided
by molecular computers and injected into the blood stream could find and destroy
cancer cells or
invading bacteria, unclog arteries, or provide oxygen when the circulation is impaired.
Formed
by special
cells that contain «attack» enzymes that can break down proteins of
invading parasites into the body, mast
cells are a component of the immune system and their unique make up makes them a distinctively behaving
cancer.