Sentences with phrase «invested significant effort»

When we started we didn't even know who those players were so I think a lot of the work of the CFC consortium has really mapped out who the players are, what are the molecular pathways that are involved in the course of disease, and we actually have invested significant effort into developing strategies and therapeutics that are going to take some time to develop and test but we think that we are well on the way to having in hand approaches that will have a significant impact.

Do these Ph.D. s hold jobs that call on their training and make it a worthwhile investment — both for the individual graduate and for the larger research enterprise, which uses public funding and invests significant effort in training them?

As well as upgrades to the engines, Hyundai has invested significant efforts in tuning the MacPherson strut (front) / multi-link (rear) suspension to better suit local roads.

Time and again, I've seen law firms invest significant effort and finances developing savvy marketing campaigns that drive traffic to their websites or phone calls to their law firms, only to drop the ball when it comes time to turn that prospective client into a paying one.

For example, many BigLaw clients are currently investing significant effort and funds into automating much of the work that has previously gone to their internal and external advisers and agencies, including lawyers.

Not exact matches

Such risks, uncertainties and other factors include, without limitation: (1) the effect of economic conditions in the industries and markets in which United Technologies and Rockwell Collins operate in the U.S. and globally and any changes therein, including financial market conditions, fluctuations in commodity prices, interest rates and foreign currency exchange rates, levels of end market demand in construction and in both the commercial and defense segments of the aerospace industry, levels of air travel, financial condition of commercial airlines, the impact of weather conditions and natural disasters and the financial condition of our customers and suppliers; (2) challenges in the development, production, delivery, support, performance and realization of the anticipated benefits of advanced technologies and new products and services; (3) the scope, nature, impact or timing of acquisition and divestiture or restructuring activity, including the pending acquisition of Rockwell Collins, including among other things integration of acquired businesses into United Technologies» existing businesses and realization of synergies and opportunities for growth and innovation; (4) future timing and levels of indebtedness, including indebtedness expected to be incurred by United Technologies in connection with the pending Rockwell Collins acquisition, and capital spending and research and development spending, including in connection with the pending Rockwell Collins acquisition; (5) future availability of credit and factors that may affect such availability, including credit market conditions and our capital structure; (6) the timing and scope of future repurchases of United Technologies» common stock, which may be suspended at any time due to various factors, including market conditions and the level of other investing activities and uses of cash, including in connection with the proposed acquisition of Rockwell; (7) delays and disruption in delivery of materials and services from suppliers; (8) company and customer - directed cost reduction efforts and restructuring costs and savings and other consequences thereof; (9) new business and investment opportunities; (10) our ability to realize the intended benefits of organizational changes; (11) the anticipated benefits of diversification and balance of operations across product lines, regions and industries; (12) the outcome of legal proceedings, investigations and other contingencies; (13) pension plan assumptions and future contributions; (14) the impact of the negotiation of collective bargaining agreements and labor disputes; (15) the effect of changes in political conditions in the U.S. and other countries in which United Technologies and Rockwell Collins operate, including the effect of changes in U.S. trade policies or the U.K.'s pending withdrawal from the EU, on general market conditions, global trade policies and currency exchange rates in the near term and beyond; (16) the effect of changes in tax (including U.S. tax reform enacted on December 22, 2017, which is commonly referred to as the Tax Cuts and Jobs Act of 2017), environmental, regulatory (including among other things import / export) and other laws and regulations in the U.S. and other countries in which United Technologies and Rockwell Collins operate; (17) the ability of United Technologies and Rockwell Collins to receive the required regulatory approvals (and the risk that such approvals may result in the imposition of conditions that could adversely affect the combined company or the expected benefits of the merger) and to satisfy the other conditions to the closing of the pending acquisition on a timely basis or at all; (18) the occurrence of events that may give rise to a right of one or both of United Technologies or Rockwell Collins to terminate the merger agreement, including in circumstances that might require Rockwell Collins to pay a termination fee of $ 695 million to United Technologies or $ 50 million of expense reimbursement; (19) negative effects of the announcement or the completion of the merger on the market price of United Technologies» and / or Rockwell Collins» common stock and / or on their respective financial performance; (20) risks related to Rockwell Collins and United Technologies being restricted in their operation of their businesses while the merger agreement is in effect; (21) risks relating to the value of the United Technologies» shares to be issued in connection with the pending Rockwell acquisition, significant merger costs and / or unknown liabilities; (22) risks associated with third party contracts containing consent and / or other provisions that may be triggered by the Rockwell merger agreement; (23) risks associated with merger - related litigation or appraisal proceedings; and (24) the ability of United Technologies and Rockwell Collins, or the combined company, to retain and hire key personnel.

In just the last few weeks, Elon Musk and Mark Zuckerberg revealed that, in their own way, each is investing time, effort, and significant money to improve our lives with neurotechnologies.

We believe our global opportunity is significant, and to address this opportunity, we intend to continue to invest in sales and marketing efforts, distribution channels, and infrastructure and personnel to support our international expansion, including establishing additional sales offices globally.

In an effort to be more insight - driven, companies are investing significant resources in extracting information from customers as effectively as possible.

In addition to being a leader in permeate production volumes, the U.S. dairy industry has also been a pioneer in investing significant research and development efforts revealing the sensory, functional and nutritional benefits of whey and milk permeate as cost - saving, flavor - enhancing and sodium - reducing food and beverage ingredients.

* Often, it is well into a transformation experiment before it can be determined that there is a problem, which could be after a significant amount of time and effort have already been invested.

«Although there are a lot of free resources available now, teachers still have to invest a significant amount of their own time and effort to find and vet these -LSB-...]

«One of the reasons behind the gap between the research and practitioner communities is the impression among teachers and school administrators that investing in social and emotional skills will involve significant additional efforts and resources.

The research found a «significant disparity» between the enormous amount of effort teachers invest in marking and a lack of evidence on ways to improve the marking process.

Of course, this is not meant to be easy but we believe that everyone can achieve positive results only if they invested significant time and effort in developing an outstanding financial profile.

The issue is, finding the latter requires significant time, effort and discipline whilst index investing is a much simpler affair!

We think an important part of that effort is our ongoing investment in making Vulkan a competitive and well - supported graphics API, as well as making sure it has first - class support on Linux platforms... we're continuing to invest significant resources in supporting the Vulkan ecosystem, tooling and driver efforts.»

And again, my position is that (1) nuclear power is not needed, since we can get all the electricity we need, and more, from renewables; (2) nuclear can not possibly be expanded enough, quickly enough to have any significant impact on reducing GHG emissions in the time frame that's needed, while renewables can be (and already are); and (3) resources invested in expanding nuclear power would be far more effectively invested in renewables and / or efficiency, and the opportunity costs of nuclear therefore mean that putting resources into nuclear power hinders rather than helps the effort to quickly reduce CO2 emissions from generating electricity.

But there are signs of a significant ratcheting up of policy ambition in the design of this scheme — and SEAI's increasing efforts to stimulate profound energy savings from Ireland's existing stock via the likes of the Deep Retrofit scheme — reflecting a recognition of the need to help Irish people to invest in high levels of energy efficiency and to replace climate - destroying fossil fuels with clean, cost - effective renewable energy sources.

While most law firms invest significant time and money in designing their websites, few make the effort to adequately promote them — and that is an opportunity.

My prediction is that we will see a significant increase in the number of law firms, both consumer and corporate - focused, investing in social advertising to enhance their social media efforts during the coming year.

On the latter count, lawyers have to invest significant time and effort, years of effort, in order to gain their credentials and to be admitted to the Bar.

To gain a competitive advantage, businesses typically invest significant time and money to develop and secure their trade secrets, such as information about manufacturing techniques, sales methods, advertising efforts, and client and supplier information.

Many firms invest significant time, effort and money in their websites, and that's a step in the right direction.

You've invested significant time and effort in your business.

Later on, there's this even more interesting bit: «We're continuing to invest significant resources in supporting the Vulkan ecosystem, tooling and driver efforts.

Some of the world's largest automakers have invested significant sums into plug - in vehicle development efforts in recent years, but Tesla Motors» (s TSLA) IPO this week gives us the first real glimpse of how the market values an electric vehicle business.

If you're investing a significant amount of your time and effort into creating a transparent work environment then it's also worthwhile that you invest some resource in transforming the workplace itself.

I recently had a childhood friend make a career change in her late thirties: she went back to school full - time, investing significant time, effort and money to turn her nursing dream into reality.

The AAP is committed to leading an invigorated, science - based effort at transforming the way our society invests in the development of all children, particularly those who face significant adversity.74

Couples who want to recover from the trauma of infidelity generally find it necessary to invest significant time and effort into rebuilding the relationship.

You will need to invest a significant amount of effort, no small amount of money, and have a bit of luck in order to actually make any money.

We intend these reports to be a source of reliable information that help renters and policymakers make sound decisions, and we invest significant time and effort in gathering and analyzing rent data.