Sentences with phrase «investigates signaling pathways»

Researchers at CEA, CNRS and Université d'Aix - Marseille have investigated a signaling pathway, scarcely studied until now, which was already present in the bacterial ancestor of chloroplast, the compartment where photosynthesis takes place.

Dr. Nguyen then worked at the Buck Institute for Research on Aging and at Stanford University, where she investigated the signaling pathways underlying neurodegeneration and how the modulation of these pathways can influence the AD phenotype.

Dr. Kulkarni's research focuses on investigating signaling pathways impacting growth and function of pancreatic islet cells with the long - term goal of improving therapeutic approaches for the treatment of type 1 and type 2 diabetes and obesity - associated conditions.

Researchers investigating signaling pathways which control pluripotency highlight newly found interactions and redundancies in mouse embryonic stem cells

With the recent development, by our group, of cell - permeant NAADP (NAADP - aceteoxymethyl ester) and a selective NAADP receptor antagonist (Ned - 19; 1 -(3 --LRB-(4 -(2 - fluorophenyl) piperazin -1-yl) methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido [3,4 - b] indole -3-carboxylic acid), the ability to investigate this signaling pathway has improved.

Not exact matches

The new research, reported Nov. 25 in the Journal of Biological Chemistry, investigated the role of two proteins, GRB10 and p70S6K, in the control of the signaling pathway that activates M2 cells.

Specifically, I am investigating how the cAMP / PKA signaling pathway affects collagen structure and deposition, using a hydrogel - based, three - dimensional culture system to create a model that is more physiologically relevant than one produced by standard two - dimensional tissue culture methods.

They also investigated if the genes were involved in any known signaling pathways.

As a postdoctoral researcher at Harvard Medical School, he investigated the use of small - molecule drugs to manipulate signaling pathways to enable otherwise senescent progenitor cells of the cochlea to divide and form new sensory cells.

Poznansky's team — with lead scientist Huabiao Chen, PhD, corresponding author of the current report — had been investigating applications of AMD3100, a drug that blocks the CXCR4 / CXCR12 signaling pathway known to be involved in cancer development and in the way in which mesothelioma evades the immune system.

In 2008, he joined the group of Caetano Reis e Sousa at the Cancer Research UK (CRUK) London Research Institute and later joined the Francis Crick Institute, where he was awarded Marie Curie and EMBO long - term postdoctoral fellowships to investigate innate immune receptors and signaling pathways that trigger dendritic cell activation and drive T - cell responses against viruses or tumors.

We are investigating the genes that are the target of this pathway, how it influences the cells of growing worms, the size differences between the sexes (hermaphrodite worms are larger than males), and the way in which it mediates signals from the environment.

My lab is investigating the normal cellular functions of signaling pathways implicated in neurological disease, with an emphasis on axon growth and guidance.

With collaborators in the biology department, Dr. Weiss applied these ultrasensitive techniques to investigate the Hedgehog signaling pathway — a critical mechanism that helps give rise to the spatial patterning in developing embryos, but has also been identified as a key culprit in up to 25 % of cancer deaths.

Insofar as kinase inhibitors interfere with signaling dynamics, and, in turn, signaling dynamics affects inhibitor responses, we investigated associations in this study between cell - specific dynamic signaling pathways and drug sensitivity.

Using imaging techniques, the cell signaling pathway can be investigated in detail to target areas that could prevent cancer from developing.

In order to investigate the mechanisms leading to improved insulin sensitivity with exercise training, it is necessary to analyze some of the components of the insulin signaling pathway in skeletal muscle.

Researchers will investigate how signaling pathways contribute to hemangiosarcoma growth, and if existing drugs can interrupt the process to reduce tumor growth and chemotherapy resistance.