Sentences with phrase «involved in different cell»

Understand the molecular mechanisms involved in different cell types and organisms to explain the differences in efficiencies

Not exact matches

Different studies suggest that bacteria present in the maternal gut could reach the mammary gland during late pregnancy and lactation through a mechanism involving gut immune cells.

Eichenbaum cautioned that there are a limited number of brain cells involved in encoding memories that are reused in different ensembles.

«Each area of the brain is different with distinct cell types and connectivity, so if we can confirm that one area of circuitry is more involved in a particular symptom than another, we may eventually be able to treat a depression patient more efficiently than treating everyone the same way.»

The new findings also showed that activation of the AIM2 inflammasome by the DNA virus cytomegalovirus does not involve IRF1, suggesting that the DNA of the invading microbes is presented to the cell in different ways.

The researchers have compared various processes involved in gene expression, such as gene transcription and chromatin modification, and have repeated this in different tissues and cell types from both humans and mice.

Although the types of nerve cells involved in the two systems maybe very different, the circuit patterns are highly likely to be similar.

The olfactory system comprises six million to 10 million receptor cells (of which there are nearly 400 different types) and links to multiple brain structures and neural pathways, including those involved in memory, emotion and movement.

Different classes of MHC molecules exist and are involved in immunity against pathogens and tumor cells as well as the formation of immune tolerance to self - antigens.

The researchers found five different sub-types of HL among the patients studied: 247 cases of the nodular sclerosis (NS) type, in which the tumour nodules are large; 105 of mixed cellularity, where a mixture of different types of inflammatory cells are involved; 58 lymphocyte rich, the sub-type with the best outcome; 68 «others»; and 143 «not otherwise specified» (NOS).

The study involved extracting Ribonucleic acid or RNA — found in the cells of all living organisms — to develop a transcriptome — the gene readouts in a cell — to examine what occurs during the different developmental stages of the cockroach pregnancy and to explore if those changes hold wider applications for other mammals.

«We found another pathway that is dysregulated, that involves the same molecule implicated before — mGluR5 — but in an entirely different way,» said Vitaly Klyachko, PhD, an associate professor of cell biology and physiology and the study's senior author.

Samples of tumours from bowel cancer patients given different doses of resveratrol showed that even lower doses can get into cancer cells and potentially affect processes involved in tumour growth.

One of the great challenges in biology involves finding ways to study different biological systems in cells simultaneously to understand how they work together to sustain life.

Brain cells from different people vary in their susceptibility to Zika infections, says infectious disease researcher Scott Weaver, also at the University of Texas Medical Branch but not involved in the study.

Many different cells are involved in the complex processes: skin cells (keratinocytes) and cells of the immune system, among others T lymphocytes, macrophages, mast cells and others.

Blocking the mechanisms involved in other methods of cell death including apoptosis and phagocytosis did not disrupt the process, confirming that entosis operates in a different way.

Not only were levels of metabolic compounds different, but the expression of certain genes involved in metabolism was turned up, and the epigenome of the cells — molecular markers on DNA that change gene expression on a broader scale — was altered.

Han et al. demonstrated that in Caco2 cells, extracellular NAD + inhibited the binding of NF - kB to DNA by blocking the transcription of different genes involved in both inflammatory and aging pathways (interlukin - 6, interlukin - 1 beta, tumor necrosis factor alpha) 27.

«By getting me involved in the project, not only could we do these biological, cell - based functional assays that Roy's lab carries out, but we could also purify the integrins or parts of (them) and do both structural and biophysical characterization of interactions — how the different subunits stick together,» he said.

This is why recent work in the field of cancer research has focused on picking apart the complex cellular pathways involved in the development of different cancers and identifying the roles of key proteins involved, with the goal of being able to discriminately and effectively eliminate cancerous cells from the body.

Rothman also proposed that SNAP - 25, VAMP / synaptobrevin and syntaxin represent members of a large family of proteins, different forms of which are involved in membrane fusion in all cells, and in different compartments within cells.

«We've always suspected that different cell types are involved in determining how a heart is built,» said GICD Director and senior author Deepak Srivastava, MD. «Our research showed that the signals from cardiac fibroblasts contribute to the different responses of cardiomyocytes.»

Research Focus: I am involved in the analysis of transcriptomic and epigenomic data in various types of human immune cells and in different diseases.

One common analysis applied to scRNA - seq data involves detecting differentially expressed (DE) genes between cells in different biological groups.

Using genetic tools to turn on and off different parts of the brain, the scientists were able to identify specific brain circuits and neurons (brain cells) involved in the food coma experience.

Zinc acts as a catalyst in about 100 different enzyme reactions required by our body and is involved in DNA synthesis, immune function, protein synthesis, and cell division.

It involves dozens of cell types and hundreds of different signalling molecules, all of which communicate in immensely complex ways.

Alpha Herpesviruses such as FHV - 1 cause disease by two distinctly different mechanisms: 1) cytolytic (cell - rupturing) disease which involves active viral replication and destroys the epithelial cells of the cornea and conjunctiva causing ulceration; and, 2) immune - mediated disease results from the deposition of viral antigen in subepithelial tissues.