Not exact matches
«Studies like the current one
involving rhabdomyosarcoma are giving us a close - up look at the way cancer evolves in response to treatment,» said study co-author Richard K. Wilson, Ph.D., director of The Genome Institute at Washington University School of Medicine in St. Louis, where scientists have extensive expertise analyzing
tumor recurrence using whole - genome
sequencing.
The latter, presented by Eric Lander of the Broad Institute in Cambridge, Massachusetts, would systematically
sequence tumor samples for mutations
involved in cancer to speed up the search for new drugs and diagnostics.
«Formation of a
tumor is driven by genetic events,» says Dr. Roe, «but its ability to spread may not
involve direct changes in the DNA
sequence.»
«Formation of a
tumor is driven by genetic events but its ability to spread may not
involve direct changes in the DNA
sequence,» says Dr. Roe.
These rearrangements
involved PGBD5 - specific signal (PSS)
sequences at their breakpoints and recurrently inactivated
tumor - suppressor genes.