Sentences with phrase «involves alterations»

Biogeographic forcing involves alterations in plant species composition.

Yet this said, Whitehead's rendering of feeling as functional is clearly not taken to involve any alteration in its substrative status.

Yet evidence suggests that conditions such as post-traumatic stress disorder, autism and dementia involve alterations in white matter.

The trio concluded that the gene was an indivisible physicochemical unit of molecular size, and they proposed that a mutation involved the alteration of a chemical bond in that molecule.

The gene's fall from leadership is the result of geneticists» growing attention to epigenetics — a form of genetic change that is essentially the gene's way of responding to its surroundings but which does not involve alterations in the gene's DNA.

Although epigenetic changes are usually temporary, they involve alterations in the proteins that bind together the long strands of DNA.

The neurobiology of Trichotillomania is poorly understood, although there is increasing evidence to suggest that TTM may involve alterations of reward processing.

The biological mechanisms of lifespan extension through calorie restriction are not fully understood, but researchers say it may involve alterations in energy metabolism (as mentioned above), reduced oxidative damage, improvements in insulin sensitivity, reduction of glycation, modulation of protein metabolism, downregulation of pro-inflammatory genes and functional changes in both neuroendocrine and autonomic nervous systems.

His work involved the alteration of the environment and repeated geometric forms, and he came to see sculpture and space as interdependent carriers of deep philosophical and emotional meanings.

The principle mechanisms involve alterations of lapse rate and decrease (increase) of large - scale cloud cover in layers that are preferentially heated (cooled).

Not exact matches

He said «several officials» at the finance ministry's division in charge of state land sales were involved in the alterations.

«It's extremely regrettable and I apologise for this,» Aso told reporters, when asked whether he felt responsible as head of the ministry involved in the alterations.

Contractors must be ready not only to make eleventh - hour changes to blueprints but also to (quickly) apprise a bevy of involved parties — vendors and subcontractors, architects and superintendents, office personnel and field personnel — of the alterations.

With the hectic schedule involved in providing quality patient care while managing staff at the same time, partnering with Infinit Healthcare for outsourced medical billing can help you manage forthcoming alterations to the system and ensure a more accurate billing of services.

Of course such an alteration involves for hierarchy and rank and file an uncomfortable period of transition: the old and well - tried is no longer there; the new has not yet got into its stride, has not yet become something that is taken for granted without discussion; the intellectual and religious attitudes necessarily required if the new institutions are to succeed have first slowly to develop.

The proper qualification of carryover acknowledges the fact that selection and alteration are involved in any process by which a thing becomes a component of another thing, modified to fit with the other components.

That the conservative judges should actually do such a thing does not involve any radical alteration in the «job description» of the justices.

The alterations will involve partial demolition of the building, refurbishments inside and the building of a new worship hall, café, foyer and meeting rooms.

While I was raised a Catholic, I do attest that, the bible is often changed to conform to each era, we have many alterations and editing that is involved, as I once sat down with a handful of bibles and compared several passages.

Minor alterations, such as were already involved in the translation from Aramaic into Greek, must also be assumed, although they can not be established in each individual case.

«The minor alterations submitted before the Legislature today involve the re-allocation of approximately $ 1.5 million out of the nearly $ 1.7 billion county budget, and if passed in full as presented today without any further amendment, will be signed into effect by me,» Poloncarz said in a statement.

Weight loss surgery can curb alterations in brain activity associated with obesity and improve cognitive function involved in planning, strategizing and organizing, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

However, Kenyon's work with worms has involved genetic alteration, an unlikely program for human longevity.

The alterations were found in the nucleus accumbens, a brain region involved in reward - related learning.

For example, the division plane at which cell division takes place is marked by correct patterning of specific proteins, and should be robust against alterations in the relative concentrations of the proteins involved.

In all, the study found and validated 76 alterations in cancer - associated genes in the cell lines, many of which are involved in activating known oncogenes including TERT, TP53 and PIK3CA.

Called structural variants, these alterations involve the insertion or deletion of entire words or sentences of the DNA code.

This cancer is associated with several alterations of the cell's DNA, but it has been unclear which gene or genes are involved in its development.

Epigenetic alterations are thought to be key molecular switches that are involved in the development of cancer.

In a report on the mouse studies, published online Sept. 11 in PNAS (Proceedings of the National Academy of Sciences of the United States of America), the investigators say the genetic alteration appears to release the biochemical «brakes» on brain cells involved in body movement, reasoning and perception of the world, triggering over-excited activity and reactions.

Epigenetics is being recognized as an increasingly important area of research that involves an understanding of the molecular mechanisms that influence the phenotypic outcome of the genome without alteration of the DNA sequence.

The tool allows researchers to explore how alterations in more than 2,000 proteins affect the diverse biological functions in which these molecules are involved.

These altered physiological parameters may be explained by alterations in markers involved in mitochondrial biogenesis and calcium kinetics.

RNAi knockdown of KMO - 1, an enzyme involved in ommochrome synthesis that is expressed in pigment cells, leads to alterations in body color and increased porphyrin levels.

Emerging evidence shows that alterations in multiple signaling pathways are involved in primary and / or secondary resistance to checkpoint inhibition.

Cytotoxicity of a mutant huntingtin fragment in yeast involves early alterations in mitochondrial OXPHOS complexes II and III.

All people have two copies of every gene, and earlier work by the researchers on identical twins with leukemia indicates that a second genetic alteration - involving the second copy of the TEL gene, one of the two so - called «alleles» — occurs post-natally to actually nudge blood cells into a leukemic state.

The first mechanism involves chemical alteration driven by the types of minerals present and by the diverse and abundant microbial community, which both stabilizes and releases carbon.

Moreover, recurrent genetic alterations within these cancers are often involved in only a small percentage of cases.

Alterations in ΔFV0.1 in the present study are parallel to similar changes in sensitivity to G6P (ΔA0.5), indicating that phosphorylation / dephosphorylation - dependent mechanisms are involved in the changes of FV0.1.

This raises the question whether senescence induced by physiological or pathological alterations may be involved in aging.

Recent estimates suggest that as many as 1.9 million children younger than 18 years have a sport - or recreation - related concussion each year in the United States.1 This injury is biomechanically induced, with symptoms resulting from neuronal dysfunction due to functional and neurometabolic alterations rather than gross structural abnormalities.2 Compared with boys involved in similar activities, girls experience higher rates of sport - related concussion,3 - 7 report more severe symptoms,8 - 11 demonstrate worse cognitive impairment,8 - 10, 12 and take longer to recover.11 The neural mechanisms behind these postconcussion sex differences are poorly understood but have been attributed to differences in neuroanatomy and physiology, 13 cerebral blood flow, 14 and the female sex hormones estrogen and progesterone.15 - 17

The alterations occurred when a segment of the NTRK genes involved in regulating cell division fused with part of another gene.

Many medical - genetic syndromes show a clear connection between genetic alteration and typical facial gestalt [49], hence genes involved in affected individuals may also contribute to normal variations in facial shape.

A variant called the nuclear stress test involves introducing a radioactive tracer into the body to visualize alterations in blood flow within the heart.

in a middle - term, exploit the experimental systems established, to identify the direct causative factors (genetic, environmental, iatrogenic) involved in the initiation of chromosomal alterations and disease progression, and to identify new therapeutic targets;

Insecticide resistance is typically associated with alterations to the insecticidal target - site or with gene expression variation at loci involved in insecticide detoxification.

[17] This involves significant alterations in the conversion of arachidonic acid to other bioactive molecules (overexpression or disturbances in the ARA enzyme cascade).

These likely contribute to inflammaging and alteration of redox status, which can exert effects on the brain through the age - related increase in bacteria involved in the tryptophan metabolism pathway; findings supported by the demonstrated reduction of tryptophan in the serum of centenarians.

At first glance, 5 % seems pretty generous — that is until you consider that this also includes what you would spend on alterations, dry cleaning, shoes, handbags and whatever other fashion essentials are involved in making you look like the glam - gal everyone knows and loves.