Sentences with phrase «involves apolipoprotein»

Not exact matches

In 1993, Poirier and his Montreal - based team co-discovered an important genetic risk factor involved in the most common form of the disease: a defective gene, called Apolipoprotein E type 4 (ApoE4), that prevents the normal transport of cholesterol and phospholipids to the brain.

In 1999, he was named an Alexander Hollaender Distinguished Fellow where he identified a novel apolipoprotein (ApoA5) involved in human and mouse triglyceride metabolism.

Involved in the initial discovery of apoE as a major apolipoprotein regulating lipoprotein metabolism, including that apoE is induced by fat / cholesterol feeding in atherogenesis.

The two most striking risk factors appear to be hyperinsulinism and possession of one or two E4 alleles for the apolipoprotein E gene (ApoE4), which is involved in lipid processing.