Sources tell Investigative Post this deal has been months in the making and far surpasses the first Billion To Buffalo deal
involving drug research, development and manufacturing at the Buffalo Niagara Medical Campus.
Not exact matches
One serious problem in the area of recombinant DNA
research is, however, that
drug companies and government agencies are as much
involved as are university professors.
The model is the basis of the state's first Buffalo Billion project, in which the state is providing $ 50 million to build and equip a facility at or near the downtown Buffalo Niagara Medical Campus to attract companies
involved in pharmaceutical
drug research and manufacturing.
The facility is
involved in
drug development and conducts clinical
research for cancer treatment.
«This well - designed set of experiments shows that chronic THC pretreatment appears to restore a significant level of diminished cognitive performance in older mice, while corroborating the opposite effect among young mice,» wrote Susan Weiss, director of the Division of Extramural
Research at the National Institute on
Drug Abuse, who was not
involved in the study, in an e-mail.
Universities are particularly sensitive to university space, resources and / or faculty being
involved in outside activities during their working hours, and also for potential conflicts of interest, in which your university
research could be biased by receiving outside funding from an inappropriate source, as when a
drug company has a vested interest in the outcome of your independent
research.
So I started to volunteer in a
research laboratory
involved with pharmacology and the responses of
drugs in the brain and how they influence behavior.
Botulinum toxin has undergone a number of reincarnations over the years, from a contaminant in improperly prepared foods, to a laboratory
research tool to probe nerve - muscle communication, to a
drug to treat problems
involving eyes, muscles, and excessive sweating to, most famously, a
drug that combats wrinkles for cosmetic purposes.
The
research involved engineering nanostructures containing both gold and cisplatin, a conventional chemotherapy
drug.
New
research involves a lot of different ways to affect the brain:
drugs, electrical signals, and, yes, actually shining light on neurons.
Among the highly publicized events was a series of spectacular and potentially lethal slip - ups
involving such gold - standard federal
research establishments as the U.S. Centers for Disease Control and Prevention (CDC) and the Food and
Drug Administration, and a hearing looking into those agencies» safety shortcomings by the House Energy and Commerce Subcommittee on Oversight and Investigations.
Some said they also kept tabs on officials
involved in
drug testing: 55 schools (70 percent) reported monitoring senior and mid-level officials responsible for hiring and firing, and 62 of them (81 percent) said they kept an eye on members of so - called institutional review boards, who approve human
research proposals.
The discovery
involved ORNL's Spallation Neutron Source, which provides the most intense pulsed neutron beams in the world for scientific
research and industrial development, and ORNL's Titan supercomputer, the nation's most powerful for open science — a one - two punch for illuminating the physical properties of potential
drugs that inform new design principles for safer, improved delivery platforms.
The National Institutes of Health is facing a new salvo from conservatives upset about
research on topics
involving sexual behavior and
drug abuse.
An essential new way to move discoveries forward has emerged in the form of multi-stakeholder collaborations
involving three or more different types of organizations, such as
drug companies, government regulators and patient groups, write Magdalini Papadaki, a
research associate, and Gigi Hirsch, a physician - entrepreneur and executive director of the MIT Center for Biomedical Innovation.
The latest work paints a picture of LSD and some other hallucinogens as
drugs that can decrease modularity and connectivity within brain networks while enhancing the brain's overall connectivity, explains Frederick Barrett, a cognitive neuroscientist at Johns Hopkins University who has studied hallucinogenic
drug effects but was not
involved in the
research released this week.
Commenting on the study, Dr Andres Poveda, Head of the Gynecological Oncology Clinic at Fundación Instituto Valenciano de Oncología, Valencia, Spain, who was not
involved in the
research, said the CIRCCa study is the second recent trial to show the benefit of adding an antiangiogenic
drug to chemotherapy in cervical cancer.
These results can serve as the foundation of future
research on the wide range of possible applications
involving microfluidic processes such as water purification and self - powered
drug delivery systems.
For the study, Ho and Kosik, leading experts in Alzheimer's
research, compiled a list of 64 conceivable approaches to
drug discovery, addressing a range of biological mechanisms that may be
involved in the disease.
The next phase of
research will
involve testing in humans, which was approved last year by Health Canada and the U.S. Food and
Drug Administration.
Drugs that target this machinery would not kill the microbes, just stop them from hanging on, so they should be less likely to provoke resistance, says David Brown of charity Antibiotic
Research UK, who was not
involved in the study.
John Rossi, a molecular biologist at the Beckman
Research Institute in Duarte, Calif., who was not involved in the research, noted that from his own work, using RNAi to treat T cells may allow patients to significantly reduce the dosage of the anti-HIV drugs — up to 1
Research Institute in Duarte, Calif., who was not
involved in the
research, noted that from his own work, using RNAi to treat T cells may allow patients to significantly reduce the dosage of the anti-HIV drugs — up to 1
research, noted that from his own work, using RNAi to treat T cells may allow patients to significantly reduce the dosage of the anti-HIV
drugs — up to 100-fold.
The
research was done with two strains of mutant mice, but the neuroscientists
involved say the results point to a target for
drugs that could potentially repair analogous damage in humans.
You are
involved in pioneering projects, designing new and innovative approaches to
drug development,» says Rainer Constien, a molecular biologist and former
research scientist at Munich - based Ingenium Pharmaceuticals AG.
At present, the regulation of gene drive
research does not fit within the purview of any of the U.S. agencies
involved in the Coordinated Framework for the Regulation of Biotechnology, which includes the Food and
Drug Administration, U.S. Department of Agriculture, and the U.S. Environmental Protection Agency.
Professor Peter Naredi, the ECCO scientific co-chair of the Congress, who was not
involved in the
research, commented: «Although the CheckMate 067 study has already reported that a combination of two checkpoint inhibitors, nivolumab and ipilimumab, is superior to either
drug alone, the results presented here in Vienna have important clinical implications.
«RNAi therapies are a unique approach to cancer treatment as they have the potential to «turn off» the genes» coding for proteins
involved in cancer cell division,» said Ramesh K. Ramanathan, M.D., medical director of the Virginia G. Piper Cancer Center Clinical Trials Program at Scottsdale Healthcare and deputy director of the Clinical Translational
Research Division of the Translational Genomics
Research Institute (TGen) in Phoenix, Ariz. «Using a lipid nanoparticle, the RNAi
drug can be delivered to a cancer cell to block the expression of specific proteins
involved in tumor growth.»
Dr. Ghavami joined PsychoGenics in 2007 and directs molecular biology and electrophysiology groups and has been extensively
involved in
drug discovery
research.
In addition to testing the safety and effectiveness of the newest
drug therapies targeting GIST, physicians here are actively
involved in
research to fine - tune usage of standard
drugs in treating GIST.
deCODE's genetic
research is aimed at identifying the genetic factors
involved, as a means of identifying new
drug and diagnostic targets that can target the underlying cause of disease and point the way towards more effective treatment and prevention strategies.
Initial work at the firm will
involve research into a particular
drug that, according to tests, can double the rate at which complex tissues in zebrafish regrow after amputation.
It seems to be a welcome addition to what those of us
involved in targeted
drug delivery
research for the last 10 years would recognise as part of this field.
The KININ meeting occurs every three years, assembling scientists and clinicians
involved in the field of bradykinin (kinins) and its related proteins (enzymes, cofactors, substrates, receptors, proteolytic systems, disease states, and developing therapies) for presentation of the latest ideas,
research,
drug development and therapeutics in these biologic systems.
Küster's
research involves studying interactions between
drug molecules and protein populations in cells.
He conducts
research on diabetes and has been
involved in developing new
drugs to treat type 2 diabetes.
Previous
research suggests that adiabatic quantum computers are especially good at optimization problems, which
involve finding the best solution from all feasible solutions, such as the shortest route connecting multiple destinations, or the most stable form of molecules — the former problem could help Mars rovers better explore the red planet, while the latter could lead to better
drugs or catalysts.
Translational
research is a high - risk, iterative phase of the
drug development pipeline that
involves a lot of trial and error to assess if the
drug...
The same brain structures implicated in the urge to take
drugs are
involved in other biological urges, Paulus added, suggesting that a homeostatic approach could have a broad impact on treatments that seek to control addictions or psychiatric disorders, and will lay the groundwork for new areas of
research.
We have done so via the National Cooperative
Drug Discovery / Development Group (NCDDG) Program
involving a multidisciplinary
research partnership to discover superior agents to treat mental illness.
Most therapeutic
research involving the testing of new
drugs is conducted in highly regulated phases that study dosage, safety, efficacy and long - term side effects:
Pairing memantine with a cholinesterase inhibitor, a type of
drug that prevents the breakdown of neurotransmitters
involved in memory, has become a standard treatment for mild Alzheimer's disease, but this study «clearly flies in the face» of that approach, says William Thies, PhD, the chief medical and scientific officer of the Alzheimer's Association, a
research and advocacy organization based in Chicago.
In addition to being an astute clinician, Dr. Rosenberg is a
research scientist, and is actively
involved in the development of
drugs and techniques to combat cancer, obesity, and age - related diseases.
Bronson spends her days managing the care of cancer patients
involved in clinical trials,
research exploring everything from new
drugs that haven't yet been approved by the FDA to new uses for current
drugs.
Although a depressed person needs to take an SSRI for weeks or even months to see results, women who take the
drugs for hot flashes notice a difference within a week or even right away, says Dr. Loprinzi, who has conducted several studies on antidepressant
drugs for hot flashes but was not
involved in the new
research.
She has been
involved in school - and community - based
research including student and staff wellbeing, bullying intervention and prevention, cybersafety promotion, physical activity promotion, road safety, mental health promotion, violence prevention, and tobacco, alcohol and other
drug use prevention.
Of Dreamers and
Drug Mules: Rep. King on the DREAM Act Tampa Bay Times, July 26, 2013 «In a decade of
research, Gonzales has found only a tiny percentage of undocumented immigrants got
involved with crime, much less stayed
involved with crime.
During his academic time he had a particular interest in high - quality
research and
research appraisal, enrolling in a Masters degree program in Epidemiology, being
involved in veterinary clinical trials of novel
drugs to treat cardiac disease, and becoming cardiology associate editor for both the Journal of Small Animal Practice and Veterinary Medicine and Science, as well as being a member of the external review board for the Journal of Veterinary Cardiology.
This sounds familiar — similar to the scandal of non-repeatability that has exploded in the life sciences, that is, medical
drug discovery
research especially
involving molecular genetics.
In the field of life sciences, he has successfully litigated major cases
involving recombinant DNA, monoclonal antibodies, fusion proteins, siRNAs, small molecule compounds,
drug delivery, molecular diagnostics,
research tool patents, and medical devices.
A. Based on my experience as well as
research I have done and the sessions I have had with experts and people who have been
involved in this type of activity, the type of bundling that was observed there with the elastic bands and the small denominations is indicative of it being
involved in proceeds of crime and in particular of the
drug trade in my mind.