Sentences with phrase «involving knockout mice»

Not exact matches

Based primarily at Harvard with Maniatis, tenOever developed a knockout mouse model to study a particular protein, IKKε, that's involved in the immune response to viral infection.

Suspecting that a protein called Ggamma13 might be involved, the research team engineered mice to be lacking this protein and then tested how the «knockout» mice responded to odors.

The process used by NIH to select the mouse lines involved a rigorous scientific review process that evaluated information on the knocked out gene, the reliability of the method used to produce the knockout, and whether the mouse line possesses a «reporter» gene, which enables researchers to analyze the pattern of the knockout gene's expression in various mouse tissues.

Under the license agreement with Lexicon, researchers who receive the knockout mice lines through NIH are free to publish any results from research involving the line and also to seek patent or other intellectual property protection for any of the inventions or discoveries resulting from such research.

Her current project involves examining neurodevelopmental changes in mGluR5 conditional knockout mice.