Sentences with phrase «ion channel into»

To get around this problem, neurobiologists Susana Lima and Gero Miesenböck of the Yale University School of Medicine in New Haven, Connecticut, inserted a gene that codes for a rat ion channel into Drosophila fruit flies.

The therapy employs a virus to insert a gene for a common ion channel into normally blind cells of the retina that survive after the light - responsive rod and cone photoreceptor cells die as a result of diseases such as retinitis pigmentosa.

They also inserted the light - sensitive ion channels into a different set of neurons in the medulla: glutamatergic neurons, which release the neurotransmitter glutamate.

Not exact matches

Bound to the cell membrane, Na ± K+ATP ase uses the energy of adenosine triphosphate (ATP) molecules to pump sodium out of the cell and potassium into the cell, maintaining a charge gradient that allows ions to flow through open channels.

It is controlled, in part, by a series of channels on the surface of heart cells that regulate the movement of different ions into and out of the cells.

(Ion channels are passages through a cell's membrane that allow charged particles, or ions, into or out of the cell.)

An ultraviolet laser frees the ATP, allowing it to rush into the ion channels of the modified neurons.

Motor rotation is powered by proton flow into the cell via ion channels.

In mammals, proteins called ion channels embedded in the cell membrane translate temperature information into electrical signals that activate nerve cells.

This small protein molecule contains a loop which fits, like a key in a lock, into the ion channel proteins found on nerve cell membranes, which are used to transport sodium and potassium ions in and out of the cell.

Researchers at Johns Hopkins have spotted a strong family trait in two distant relatives: The channels that permit entry of sodium and calcium ions into cells turn out to share similar means for regulating ion intake, they say.

This stretching can activate calcium ion channels, causing a neuron to fire, or can signal the body's repair mechanisms to crank into overdrive.

This enabled them to «smuggle» calcium ions into cells and see what happened to sodium channels when the calcium concentration changed abruptly.

Using a device engineered by Nan Marie Jokerst, Ph.D., a professor of electrical and computer engineering at Duke's Pratt School of Engineering, the researchers showed that UVB caused calcium to flow into the skin cells, but only when the TRPV4 ion channel was present.

The virus inserts the therapeutic gene into the cell's DNA and uses its instructions to produce a receptor protein — a modified version of a common glutamate receptor ion channel - that they display on their surface.

As soon as these cells are exposed to light, the channels open and positively charged ions flow into the muscle cell, which then contracts.

Such ion channels are often involved in transmitting signals into cells.

Whereas in the nematode experiment the researchers targeted nanoparticles to temperature - sensitive ion channels that naturally exist in the membranes of the worms» nerve cells, the scientists inserted the gene for a heat - activated ion channel called TRPV1 into the human and rat cells.

The channels allow charged atoms and molecules to travel into or out of cells; the extra channels enabled ions to cross more easily, thereby reducing how polarized these cells had become.

The SCN5A protein winds through the membrane of heart muscle cells, forming a channel that opens to let sodium ions flow into the cells.

Like a type of door, sodium channels allow sodium ions to flow into nerve cells through tiny pores.

When light is shone on the neuron, the channel opens up and allows electrical ions to flow into the cell; a bit like a battery being charged by a solar cell.

In the system, nanoparticles injected into the brain convert a gentle, external magnetic field into heat, which triggers heat - sensitive ion channels that have been genetically engineered into neurons.

Together, these findings have brought into focus the central role of ion - conducting channels in sustaining normal cellular function and enabled fine - grained analysis of conditions in which the channels go awry.

What he found was that this switch, called an ion channel, controls the flow of calcium into immune cells called macrophages.

Mutations for mammoth hemoglobin, extra hair growth, fat production, down to nuanced climate adaptations such as slightly altered sodium ion channels in cell membranes have already been engineered into fibroblast cell lines.

GABA receptors are spread out throughout the brain and they are ligand - activated chloride channels that when activated, allow the negatively charged chloride ions across the cell membrane and into the cell where they reduce cellular activity.