Sentences with phrase «ion channel opening»

By placing lysine at specific locations, the voltage sensor can be stabilized in different conformations, which enables a dissection of voltage sensor movements and their relation to ion channel opening.

Not exact matches

Bound to the cell membrane, Na ± K+ATP ase uses the energy of adenosine triphosphate (ATP) molecules to pump sodium out of the cell and potassium into the cell, maintaining a charge gradient that allows ions to flow through open channels.

Fast - acting neurotransmitters, e.g., glutamate (excitatory) and γ - aminobutyric acid (GABA)(inhibitory), achieve effects on their target cells within one millisecond by virtue of opening ligand - operated ion channels.

When Lin's team repeated their experiment with nerve cells, they found that stimulating the quantum dots caused ion channels to open and the nerve cell to fire.

In nerve cells, opening ion channels is a crucial step in generating action potentials — the signals by which the cells communicate in the brain.

Thanks to past research he'd read about how random vibrations could open up neural ion channels, Wyss Core Faculty member James Collins discovered that those vibrations could improve seniors» motor control and balance when applied imperceptibly to soles of their feet.

«In this current study, we've shown that by opening the TRPV1 channel to allow calcium ions to enter the cell, we can turn on a gene.

When stimulated, the cells» channels open up within microseconds, much faster than most other ion channels in the body.

When the neuron gets a cue, gates on sodium channels are thrown open, ions rush in, and the voltage surges.

The binding of positively charged calcium ions in its vicinity opens the channel and allows negatively charged chloride ions to permeate across the membrane.

The conventional view is that neurons fire when a channel within the cell membrane opens, flooding the neuron with positively charged ions.

Sound waves, amplified by the outer hair cells (shown above right), vibrate the inner hair cells, opening ion channels on their surface that let neurotransmitters flow in.

Ion channels are small openings in the cell membrane of nerves that open and close like doors, in order to allow electrically charged ions to enter or exit.

Alcohol modulates the switch, technically known as an ion channel, causing it to open more frequently.

Moreover, it opens the way to study the structure and dynamics of ion channels on their biologically relevant timescales by extending it to two - dimensional infrared spectroscopy,» says Christoph Götz, PhD student in the Vaziri lab and co-author of the paper.

If this ion channel is applied to nerve cells, the channels can be opened by light, thus activating the cell.

The entering water then tilts the protein helix H2, which eventually triggers a protein - traversing open ion channel.

The pore of the ion channel is opened by removing the amino acid E90.

Ion channels are proteins found in a cell's membrane, which create tiny openings in the membrane that regulate the movement of specific ions.

Researchers have known for decades that some microorganisms, such as single - celled green algae, have proteins that respond to light by opening a channel in the microbe's membranes, allowing the passage of electrically charged ions (such as calcium and sodium).

As soon as these cells are exposed to light, the channels open and positively charged ions flow into the muscle cell, which then contracts.

Photoswitches — chemicals that change shape when hit with light - are then attached to the ion channels to make them open in response to light, activating the retinal cells and restoring light sensitivity.

But the brain's skinniest neurons sometimes send out random spikes triggered by ion channel proteins» popping open accidentally.

Within the eyes, retinal ganglion cells that signal light «ON» open their ion channels directly upon transmitter release.

How this may function is anybody's guess; one theory holds that changes in Earth's magnetic field twist the magnetite chains, perhaps forcing open ion channels that send signals to the brain.

After being activated by an external signal, potassium channels open to allow ions through.

In the new study, scientists focused on temperature - sensitive ion channels that open when they become hot enough.

He further explains that most previous work primarily used tiny magnets to open ion channels by pushing or pulling them in the right manner.

They found that when the potassium channel is open, water molecules quickly bind to tiny cavities within the protein structure, where they block the channel in a state that prevents the passage of ions.

Before you can fiddle with an ion channel, you need to figure out what opens it — you have to find the right key.

When appropriately stimulated, the channels open, sodium ions flow in, and the muscle cells contract.

Previous studies had found evidence that amphotericin opens up ion channels in membranes, perhaps making them more leaky to charged atoms that could disrupt a cell.

The SCN5A protein winds through the membrane of heart muscle cells, forming a channel that opens to let sodium ions flow into the cells.

A key stage in the molecular cascade of memory formation appears to be the opening of membrane channels through which calcium ions flow.

The stretching or compression of these tissues opens ion channels in the nerve membrane, which results in a signal to the brain.

When light is shone on the neuron, the channel opens up and allows electrical ions to flow into the cell; a bit like a battery being charged by a solar cell.

When nerve cells receive a signal of pain or other sensation, the signal opens sodium channels and floods the cell with positively charged sodium ions, which positively charge the neurons until the electrochemistry changes enough to inactivate the channels and close them.

As they did, the level of calcium ions in the neuron rose sharply, suggesting that ion channels had opened and the neuron was becoming active.

A) Ion channels respond to physiological signals by opening and closing molecular gates that control the flow of ions across the membrane.

They carry several neurotransmitter binding sites which govern the opening of a transmembrane ion channel.

The channel can open and ions are able to pass through.

The protein forms an ion channel that opens in...

Her team is currently examining the ion channels that open and close to allow the flow of ions as electrical impulses pass along the nerve cell membrane.