Sentences with phrase «ion channels»

The stretching or compression of these tissues opens ion channels in the nerve membrane, which results in a signal to the brain.

These events are directed by specialized proteins called ion channels that allow the flow of calcium ions in and out of cells and among cell compartments.

The technique involves inserting a light - sensitive ion channel into specific types of neurons by means of a virus.

He further explains that most previous work primarily used tiny magnets to open ion channels by pushing or pulling them in the right manner.

This triggers reactions such as the opening of the potassium ion channels located in the cell membrane, which causes potassium ions to flow out of the cell.

The researchers bound nanoparticles to cell membranes and used magnetic fields to heat the nanoparticles, which in turn switched open the heat - activated ion channels embedded in the cell membranes.

For years, scientists have been unsure how calcium ion channels function.

By treating the animals with drugs that target specific ion channels, the researchers could restore normal patterns to ensure healthy brain growth, rescuing the brain from its genetic fate.

Finally, we have begun to study how ion channels of polar organisms have evolved to function at or below freezing temperatures.

The researchers have investigated the effect of the substances on a potassium ion channel from fruit flies.

Different ion channels respond to different kinds of stimulation.

They use charge in the form of ions to carry energy and information — ion channels control the flow of ions across cell membranes.

His team has been working on making systems that mimic natural ion channels, for example, but much bigger so that they can transport entire molecules.

The valves are located within ion channels in cell membranes.

In the new study, scientists focused on temperature - sensitive ion channels that open when they become hot enough.

Moreover, it opens the way to study the structure and dynamics of ion channels on their biologically relevant timescales by extending it to two - dimensional infrared spectroscopy,» says Christoph Götz, PhD student in the Vaziri lab and co-author of the paper.

The Fluc family of fluoride ion channels were recently discovered, and studies by a team led by Christopher Miller, PhD, HHMI Investigator and professor of biochemistry at Brandeis University, found that they are among the most selective channels yet identified.

Evidence indicated the reverse - polarity current seen developmentally was a manifestation of the same ion channel as that evident under abnormal conditions in Tmc mutants or after tip - link destruction.

Those fluctuations showed up at every step in the neurons» functioning, from the unreliable absorption of light by pigment molecules to the sporadic opening of electricity - conducting proteins called ion channels on the neurons» surfaces.

Structure of heat - sensitive ion channel TRPV1, the receptor for capsaicin, the active ingredient in hot chile pepper.

«Biologically powered chip created: System combines biological ion channels with solid - state transistors to create a new kind of electronics.»

Not only are physiological biomaterials and live cells able to be imaged with Park SICM, but various pipette - based applications can be integrated into the investigation such as patch clamping for ion channel signal detection, electrochemical reaction analyses, and even nanoinjections or nanobiopsies.

Mice generated from embryonic stem cells in which ion channel genes have been mutated by homologous recombination often have a perfectly normal heart.

This method is directly applicable to sodium, calcium, and other ion channels where inhibitor or modulatory proteins bind with high affinity.

«Fastest measurements ever made of ion channel proteins.»

«Scientists have been measuring single ion channels using large rack - mount electronic systems for the last 30 years,» says Jacob Rosenstein, the lead author on the paper.

Co-author Fred Reike, who specialises in retinal disease, says that quantum dots have great potential in this area because they directly affect ion channels, which play a key part in the signalling pathways of vision.

BK channels are potassium ion channels found on the surface of a variety of cell types that are essential for the regulation of several key physiological processes, including smooth muscle tone and neuronal excitability.

Monobodies were engineered to function as «crystallization chaperones» that stabilized and aligned fluoride ion channels so their structure could be determined.

Four HCN genes that code for proteins which form ion channels in neurons could be involved, because these channels are vital for electrical signalling in nerves.

Every cell expresses ion channels, but the most common cells to study with patch - clamp techniques...

Epilepsy is a common neurological disorder, and mutations in genes encoding ion channels or neurotransmitter receptors are frequent causes of monogenic forms of epilepsy.

Dr. White and his colleagues had previously identified a key cellular factor — known to be a specific voltage-gated sodium ion channel — involved in that non-opioid process of pain nerve stimulation.

Amiodarone is known to specifically block ion channels, which suggests that the effect seen in the drug treated samples is specific to amiodarone HCL activity.

We also utilise a number of optical methods including single cell imaging and photo - activated ion channels such as Channelrhodopsins.

Many cells in the BLA possess acid - sensing ion channels called ASIC1a, which respond to pH changes in the environment outside of the cell.

Erwin Neher and Bert Sakmann received the Nobel Prize in Physiology or Medicine in 1991 for their development of the patch - clamp technique, which records currents coursing through single ion channels in cells.

Magnesium helps reduce hyper excitability in the central nervous system by regulating concentrations of calcium, potassium and sodium via ion channels in nerve cells.

To get around this problem, neurobiologists Susana Lima and Gero Miesenböck of the Yale University School of Medicine in New Haven, Connecticut, inserted a gene that codes for a rat ion channel into Drosophila fruit flies.

New research has identified new molecules that could help in the fight to prevent diseases caused by faulty ion channels, such as cystic fibrosis.

In flies made to express the rat ion channel in their dopaminergic neurons, which influence the fly's walking, the laser caused sedentary flies to become hyperactive.

Scientists injected into the VMHvl on one side of the animal stunted viruses carrying a modified piece of DNA engineered to encode a photosensitive ion channel selective to blue light.

They used carbon nanotube porins (CNTPs), a technology they developed earlier at LLNL, which uses carbon nanotubes embedded in the lipid membrane to mimic biological ion channel functionality.

The N - methyl d - aspartate (NMDA) receptor subtype of glutamate-gated ion channels possesses high calcium permeability and unique voltage - dependent sensitivity to magnesium and is modulated by glycine.

They set pH. Not surprisingly, protons do not cross cell membranes; they must be transported across the membrane through special proteins like ion channels.

«Our results suggest that the drugs currently used to treat childhood epilepsy — ion channel modulators — might have a beneficial effect on individuals with autism, if given at the right time, between 9 and 24 months of age,» says Wittkowski.

The ETH researchers practised on the membrane protein called GLIC (Gloeobacter ligand-gated ion channel), which comes from bacteria.