Sentences with phrase «ion channels such»

We also utilise a number of optical methods including single cell imaging and photo - activated ion channels such as Channelrhodopsins.

The basis of this technique is to genetically modify neurons to express light - sensitive ion channels such as excitatory channelrhodopsin or inhibitory halorhodospin and then use light to control the on / off status of neuronal excitation.

Not exact matches

It was commissioned by Roderick MacKinnon, who shared the Nobel prize in 2003 for his work describing the structural and mechanistic properties of such channels, which are tunnels that regulate the flow of ions across cellular membranes.

If the three - dimensional structures of the herb elements are elucidated, and a database of them can be established, it may facilitate computer - assisted imitation of docking between the herb element and physiologically important cell membrane proteins such as receptors, ion channels, and transporters.

«Monobodies are refined and powerful enough to attack important questions in biology and medicine, such as the structure of the fluoride ion channel, but they can also be used to generate molecules that are almost immediately useful in industry.

Since neurons can be depolarized by calcium and other positively charged ions, such as those the TRPV1 channel controls, we hope that this system may be effective at regulating neural activity.»

No ion channels — at least not any that had been studied to date — could produce such acute temperature sensitivity.

All such previously known molecules bind to locations at the ion channel itself.

New research has identified new molecules that could help in the fight to prevent diseases caused by faulty ion channels, such as cystic fibrosis.

Researchers have known for decades that some microorganisms, such as single - celled green algae, have proteins that respond to light by opening a channel in the microbe's membranes, allowing the passage of electrically charged ions (such as calcium and sodium).

The therapy employs a virus to insert a gene for a common ion channel into normally blind cells of the retina that survive after the light - responsive rod and cone photoreceptor cells die as a result of diseases such as retinitis pigmentosa.

TRPV4 is an ion channel, a gateway in the cell membrane that rapidly lets in positively charged ions such as calcium and sodium.

In ICP, a liquid with charged and neutral ions, such as seawater, is run through a channel.

Such ion channels are often involved in transmitting signals into cells.

Ion channels play a critical role in physiology and many different biological processes such as neuronal signal transmission, muscle contraction, or T - cell activation.

This work, published in the journal Nature, may help drive the discovery of new drugs such as local anesthetics and antiarrhythmics, which directly target this ion channel.

Mutations for mammoth hemoglobin, extra hair growth, fat production, down to nuanced climate adaptations such as slightly altered sodium ion channels in cell membranes have already been engineered into fibroblast cell lines.

The Lexicon efforts are focused on gene families that are pharmaceutically important, such as transporters, G - protein coupled receptors (GPCRs), ion channels, kinases and other key enzymes, membrane proteins (e.g., receptors), and secreted proteins.

ëinhibitory effect of metal ions, alone or combined, on sodium channels (research indicate that body's radical quenchers like glutathione, L - cysteine and EDTA can prevent or reverse such inhibition by «friendly» metals like zinc, copper, iron and cobalt, but not that caused by heavy «metals like lead and mercury), possible inhibition of sodium channel activity by dopamine, and others.