"Ion selectivity" refers to the ability of something, such as a membrane or a channel, to selectively allow certain ions to pass through while blocking others.
Full definition
These findings demonstrate that the ability of the channel to adapt its structure differently to K + and Na + is a fundamental aspect
of ion selectivity, as is the ability of multiple K + ions to compete effectively with Na + for the conductive filter.
This could be interpreted as UNC - 7L and UNC - 9 forming heteromeric channels,
with ion selectivity properties that are influenced by both isoforms (as this dictates the rectification of Gj0), but Vj gating properties dominated by UNC - 7L (as this dictates the shape of the Gj ∞ plot).
Despite a large body of work, the exact molecular details
underlying ion selectivity and transport of the potassium channel remain unclear.
Solvent responsive silica composite nanofiltration membrane with controlled pores and
improved ion selectivity for vanadium flow battery application.
Such rectifying behavior has been reported for some connexins, and has been shown to arise from the pairing of two hemichannels with
different ion selectivities [34].
The team's technique uses a metal - organic - framework membrane that mimics the filtering function, or «
ion selectivity,» of biological cell membranes.
Hence AMPA and NMDA receptor channels contain common structural motifs in their TM2 segments that are responsible for some of
their ion selectivity and conductance properties.
The mutation resulted in a lower single channel conductance for calcium and a strongly increased conductance for sodium and potassium, indicating that glutamic acid - 95 is a crucial constituent of
the ion selectivity filter.
The methionine that is key for
the ion selectivity is labelled (Met).
To unravel the structural basis for
this ion selectivity, Ines Ehrnstorfer has determined the structure of a close bacterial homologue of DMT1 by X-ray crystallography.