Sentences with phrase «ipilimumab significantly»

The phase III CheckMate 067 trial, which included 945 untreated melanoma patients, found that nivolumab alone and in combination with ipilimumab significantly improved progression - free survival (PFS) and the overall response rate (ORR) compared with ipilimumab alone.

As reported in 2015, the study met its primary endpoint after a median follow up of 2.3 years, with ipilimumab significantly improving recurrence - free survival.2 The drug was subsequently approved by the US Food and Drug Administration as adjuvant therapy for stage III melanoma.

Not exact matches

Ipilimumab as adjuvant therapy significantly improves overall survival in patients with high risk stage III melanoma, according to the EORTC 18071 phase III trial results presented for the first time at the ESMO 2016 Congress in Copenhagen.