Sentences with phrase «iron homeostasis»
"Iron homeostasis" refers to the balance or control of iron levels in the body. It ensures that the amount of iron taken in through diet and absorbed by the body is regulated, preventing deficiency or excess of this essential nutrient. Full definition
It is a bioactive molecule that helps in regulating iron homeostasis in the body.
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This review focuses on the discovery of erythroferrone and recent advances in understanding the role of this hormone in the regulation of iron homeostasis during states of increased erythropoietic demand.
Like this, the researchers from Jena, Berlin and Duisburg - Essen were able to conclude that lifespan extension in rodents can be attributed to changes in their defense against free radicals, iron homeostasis as well as cellular respiration and translation as central parts of the growth program.
They further posited that a compound called «Ferric - uptake regulator,» or Fur, which is known to control intracellular iron homeostasis in many other species of bacteria, functioned similarly in C. difficile.
She explained that the forms of iron which are soluble are different under aerobic versus anaerobic conditions, and that little work on bacterial iron homeostasis has been done in strict anaerobes, such as C. difficile.
Bach1 is a member of the BTB and CNC transcriptional regulator family that, like Nrf2, binds to ARE sequences as heterodimeric complexes with small Maf proteins [18] A major physiological role for Bach1 is in iron homeostasis through regulation of the expression of heme oxygenase - 1 (HMOX1), ferroportin (FPN1) and Ferritin (FTH) genes [23], [24], [33], [41].
You must aim for iron homeostasis to keep yourself healthy.
We are part on the newly launched NIHR Blood and Transplant Research Unit in Donor Health and Genomics, where we coordinate theme 1 - Determinants of donation - related biomarkers.This theme will address the NIHR BTRU mandate to identify and characterise «genetic, biochemical, lifestyle and other determinants of relevant blood cell traits... and measures of iron homeostasis, including determinants of the trajectories of these factors over time among donors».
Iron homeostasis in the metabolic syndrome.
The acute phase response to infection and inflammation induces alterations in iron homeostasis that reduce iron supplies to pathogens.
IRP - 1 is an mRNA - binding protein that represses the expression of various proteins involved in iron homeostasis.