Sentences with phrase «irradiating cells»

Apparently, the irradiated cells pass on a distress signal or emit some chemical that breaks the DNA of neighboring cells (ScienceNOW, 7 September 2005).

Ionizing radiation is a potent DNA damaging agent that interacts with cellular DNA and induces lesions in the irradiated cells and prevents cell proliferation and induces cell death by apoptosis or necrosis depending on the radiation dose.

Astaxanthin has been shown, when take in concordance with other carotenoids, to protect against free radical induced DNA damage, repair UVA - Irradiated cells, and inhibit inflammatory cell infiltration.

Not exact matches

(D) When accounting for the reduced efficiency in adherence, the cancer cells display a similar inefficiency in their ability in invade through the collagen of irradiated matrices relative to controls.

«Ionizing radiation found to soften tumor cell microenvironment: When irradiated, less stiff extracellular matrices reduced cancer growth and migration, bolstering the case to further understand fractionated radiation therapy.»

The team tested the idea by irradiating mice to eliminate their T cells.

The cell is irradiated with 1000W / m2 of light at a temperature of 25 °C, mimicking the conditions of the midday sun, and its power output is measured.

Wyrick and WSU colleagues Peng Mao, Michael Smerdon and Steven Roberts irradiated yeast cells and looked for patterns of damage at the level of individual base pairs, the DNA building blocks whose order serves as an organism's blueprint.

Ringer's lactate solution (Lactec) was irradiated with plasma for 3 - 5 minutes, after which it demonstrated anti-tumor effects on brain tumor cells.

Any glowing areas that can't be cut out are given phototherapy — irradiated with a near infrared laser, which causes the nanoparticles to heat up and kill the residual cancer cells.

When the team irradiated these mice, the tumor cells decreased or disappeared and 50 % of the mice survived the 140 - day study.

The only blood components that contain DNA are white blood cells, but blood banks routinely irradiate donor pints with gamma rays to kill off these cells because they can trigger a rejection response in their new host.

Then they go around the body and kill the cancer cells in the distant site that has not been irradiated with the light.»

The bonding properties of the saccharide coating can now be switched using this method: if the researchers irradiate their system with light with a wavelength of 365 nanometres, considerably fewer pathogenic bacteria cells can adhere to the synthetic surface.

When the team injected the shielded mice with a chemical that blocks cell - to - cell communication before irradiating them, they detected no DNA breaks and the amount of apoptosis decreased more than threefold.

To test whether adipose tissue F4 / 80 + cells shared a common bone marrow origin with other tissue macrophage populations, we transplanted bone marrow from C57BL / 6J mice expressing the CD45.1 leukocyte marker into 6 - week - old lethally irradiated C57BL / 6J mice expressing the CD45.2 leukocyte marker.

Photosensitizer effect of 9 - hydroxypheophorbide a on diode laser - irradiated laryngeal cancer cells: Oxidative stress - directed cell death and migration suppression.

First, the MimEX ™ Cell Plating Procedure is used to maintain a uniform irradiated fibroblast monolayer for the rapid clonal expansion and efficient differentiation of tissue - specific adult epithelial stem cells.

Briefly, single - cell suspensions of C57BL / 6 KO and wild - type lymphocytes, which had undergone a 96 hr in vitro boost with γ - irradiated (3,000 rad) BALB / c stimulator lymphocytes, were added to 96 - well microtiter plates (Corning Inc., Corning, NY) along with 2 × 104 51Cr - labeled BALB / c corneal epithelial or endothelial cells in a total volume of 200 μl / well.

Spleen cells (3 × 107) from either experimental or control effector lymphocytes were dispensed into 75 - cm2 tissue culture flasks along with 20 ml of boosting medium and 6 × 105 γ - irradiated (3,000 rad) BALB / c spleen cells (erythrocytes lysed).

Drew Pardoll, Glenn Dranoff, Elizabeth Jaffee, Hyam Levitsky, and colleagues conduct preclinical studies showing that a vaccine composed of tumor cells irradiated and genetically modified to produce immune system growth factor GM - CSF (granulocyte - macrophage colony - stimulating factor)-- which would become known as the therapeutic cancer vaccine GVAX — could induce potent, specific, and long - lasting anti-tumor immunity in multiple mouse tumor models.

In one recent experiment, these microcrystals were actually still inside a bacterial cell when they were irradiated.

As it was the case among irradiated wild - type mice, the predominant tumors induced by radiation in p21 - null mice were T - cell lymphomas (Table 3) ⇓.

When injected into a tumor and irradiated with near - infrared laser light, the nanoflowers heat up and kill the cancer cells around...

After 24 h, cells were irradiated as explained earlier.

Under a Westinghouse contract, NAC provided comprehensive services to transport irradiated fuel from Exelon's Braidwood nuclear power plant (Illinois) to the Studsvik hot cell in Sweden for post-irradiation examination.

Unfortunately, inclusion of the 2i in our culture system resulted in massive death of irradiated MEF cells plated at a relatively low density, suggesting that the 2i strategy might not be compatible with irradiated MEF cells.

As illustrated in Figure 2C, on the second day, the infected NPCs were replated onto irradiated HFF cells in the HFF medium.

This differentiation is triggered by the endogenous Notch inhibitor Numb, which is upregulated in the stem cells by Wnt7a derived from UV - irradiated keratinocytes.

Sorted human ILC3s (Lin - CD127 +) were cultured at 2,000 — 5,000 cells per well of a 96 well plate with irradiated (30 Gy) OP9 - DL1 feeders [70].

The hESC colonies were mechanically divided and seeded as small aggregates onto 12 - well plates (CellBIND Surface, Corning, Inc., Corning, NY), containing gamma - irradiated human foreskin fibroblasts (CRL - 2429, ATCC, Manassas, VA) as feeder cells.

(E and F) Lethally irradiated BALB / c mice were transplanted with 5 × 106 TCD - BM plus 1 × 106 total spleen T cells or CD25 - depleted T cells from B6 mice.

Lethally irradiated BALB / c mice were transplanted with 5 × 106 B6 TCD - BM cells with or without 1 × 106 B6 spleen T cells.

«This supports the idea that you could do this and get these cells in the brain without having to irradiate, which is a huge step forward in terms of making it feasible.»

Cells were cultured on irradiated mouse embryonic fibroblasts (MEF) in DMEM / F12 culture medium supplemented with KnockOut serum replacer (20 %), non-essential amino acids (0.1 mM), L - glutamine (1 mM), ß - mercaptoethanol (0.1 mM) and 100 ng / ml zebrafish basic fibroblast growth factor.

To determine whether HPCs stimulate allogenic T cells, MRL splenocytes were co-cultured with irradiated 129SvJ splenocytes, HPCs, or bone marrow cells.

Within the area irradiated with laser pulses (shown within a dashed line in Figure 8B, C) we discovered that only the cancer cell was damaged.

The Effect of p53 Status of Tumor Cells on Radiosensitivity of Irradiated Tumors With Carbon - Ion Beams Compared With γ - Rays or Reactor Neutron Beams

Bone marrow cells from CD45.1 Gasp + / + mice were injected into lethally irradiated CD45.2 Gasp − / − mice or vice versa.

After irradiating the tumor, veterinarians collect a particular type of the dog's white blood cells, known as Natural Killer (NK) cells, then stimulate and grow the cells in a laboratory before injecting them back into the dog's tumor.

We also performed several experiments to evaluate whether these second - generation feeder cells can be irradiated, frozen and then thawed prior to their effective use in B cell generation.

Therefore, we will continue to generate CD40 - B cell vaccines using freshly irradiated feeder cells.