Sentences with phrase «irreversible change in»

But there has been a secular and irreversible change in the dynamics of the legal industry — a tectonic shift from a sellers» to a buyers» market that has transformed the very basis of industry rivalry.

Susskind cites technology as the driver of this change, and in his latest book The Future of the Professions, he proclaims that «we are on the brink of a period of fundamental and irreversible change in the way that the expertise of these specialists [professionals] is made available in society.»

A shift in geologic epoch signifies an irreversible change in this planet's history, whether the icy ages of the Pleistocene or the long summer of the Holocene.

It is possible that some irreversible change in biochemistry gives the alcoholic a sensitivity or «allergy» (as AA has long claimed) to alcohol, so that one drink sets off a chain reaction leading inevitably to a drunk.

By managing macro-economic parameters, scientists believe that - unlike previously thought - it is possible to steer an economy around irreversible changes in its complex dynamics and avert potential economic disasters.

Some of the most alarming experiments demonstrate that genetically engineered biological agents can provoke irreversible changes in the nervous system and the brain.

The consequences of such initiative were disastrous: Protected from hunting for 35 years, and devoid of natural predators, the beavers grew over 5,000 times their initial population, caused irreversible changes in the forest ecosystem, and started advancing over the continent.

The twin imperatives of technological advancement and counterterrorism have led to dramatic and possibly irreversible changes in what people can expect to remain of private life.

Previous research has shown that low to moderate exposure to chlorpyrifos during pregnancy can lead to irreversible changes in a child's brain.

Some of the irreversible changes in men include breast development or

Some of the irreversible changes in men include breast development or gynecomastia, and baldness.

Cats with hypertension often have irreversible changes in the rear interior portion of their eyes (their retinas) that do effect, or prevent vision.

Human - induced warming is likely to lead to large - scale and potentially irreversible changes in physical systems such as the oceans and the cryosphere (regions covered by snow or ice).

Such an increase in CO2 emissions could raise global average temperatures by 6 °C or more, resulting in significant impacts on all aspects of life and irreversible changes in the natural environment.

Within this framework, the possibility for irreversible changes in the climate system exists.

«Unless global CO2 emissions can be cut by at least 50 percent by 2050 and more thereafter, we could confront an underwater catastrophe, with irreversible changes in the makeup of our marine biodiversity,» said Rees.

In their statement, the scientific academies say the oceans have absorbed about a quarter of the carbon dioxide emitted to the atmosphere by human activities since the industrial revolution, resulting in rapid and irreversible changes in ocean chemistry.

Some, like penta - BDE and octa - BDE have been banned, but deca - BDE is still used «despite being tied to cancer, reproductive problems, irreversible changes in brain development — and being found in the breast milk of many women in the US.

Pauley and other marine biologists have shown that drastically reduced populations in marine fishes caused by overfishing may never recover because overfishing has created irreversible changes in ecosystem structure.

Not exact matches

The permanent displacement of millions of Syrians is one way in which its war and others in the region are causing irreversible changes.

The city council said it needs time to consider zoning laws and lighting regulations «before commercial cryptocurrency mining operations results in irreversible change to the character and direction of the city.»

God is true and has touched me in an irreversible way that has changed my life for the better, forever.

The complexity of our problem, in short, arises from our situation in an historical process subject to time and change, irreversible in direction, in which the past is never wholly dead, but remains unalterably part of the situation we have to face in the present.

The new language has spread horizontally to all parts of the world and is vertically sinking in the fabric of societies, operating irreversible cultural change.

But the change of scale is not enough in itself to explain the sudden and irreversible rise of the industrial phenomenon which we see taking place around us.

We need a little change arsenal wl be okey nd equal to any pouring task, bt wenger wl nt care.Let us do whatever we could to make wenger divorce arsenal, we need total nd irreversible separation, in wenger we trust is no more nd no longer efficient nd effective.WE NEED HIM OUT.Let us protest until the board consider our excuses, one out of two: either wenger shld change his irresoanable attitude, principal or whatever so called, OR he shld go, arsenal is never his parents house.Arsene prove to be an intentional stobborn nd cantankerous individual nd his attitude provide so many pains nd discomforts upon the minds of arsenal fans.

«For the sake of future generations who could be harmed by irreversible climate change, I urge New Yorkers to reject this fear mongering and uphold science against ideology,» he said in a statement.

But, you know, the idea of pulling this altogether, of wait there may be boundaries beyond which we do not want the environment to go, either because they go in to a tipping [point] and fundamentally change or because you -LSB-'ve caused][a] near - irreversible amount of damage.

Judge Coffin says the nature, facts and drivers of climate change will be central to the case — including whether there is a threshold at which the concentration of CO2 in the atmosphere reaches a tipping point locking in irreversible planetary damage.

Morrisey said in an emailed statement that the comments to DEP «further demonstrate the need for an immediate stay of the illegal Power Plan, a plan already causing real and irreversible changes on the ground in the states.»

China once kept its doors closed to outside influences, but today the changes in China seem irreversible.

It could be if you wait too long, the changes in your heart are irreversible.»

Many people have concerns about the possible use of genome editing in humans, for example, about the risks of unintended effects due to off target DNA alterations, and the implications of making irreversible changes that will be passed on to future generations.

For those who aren't familiar with it, the «tipping point» is a concept from epidemiology (popularized by the best - selling book by Malcolm Gladwell) that suggests that small changes accumulate innocuously until a critical mass is reached, at which point a large - scale, irreversible change occurs in the system under study.

Only in specific cases are changes to the material irreversible.

These changes, the report notes, will place increasing stress on water, health, energy and transportation systems and have, in several instances, already crossed tipping points to irreversible change.

Anthracycline drugs, such as doxorubicin, are known to cause heart failure because they cause changes in the DNA structure of the heart muscle cells, leading to irreversible cardiac damage.

This sector of Antarctica has long been identified as the most vulnerable to changes in climate and, according to recent assessments, its glaciers may have passed a point of irreversible retreat.

Pesticides still abound, we're in the midst of a human - made mass extinction and decades of warnings about irreversible climate change appear to have fallen on deaf ears.

This light was no more than a flash because, along with the electrical excitation of the silicon skeleton, irreversible chemical changes take place: the internal surface of the pores is immediately covered in a layer of insulating silicon oxide, which stops further electrical excitation.

The draft report says it is «very likely» that the past three decades have all been warmer than any time in the past 800 years; that we could see almost 9 °C of warming by 2300; and that «a large fraction of climate change is largely irreversible on human timescales».

The most common cause of dementia is Alzheimer's disease, a progressive, irreversible brain disease that results in impaired cognitive functioning and other behavioural changes.

Ecosystem - based approaches provide an important route to sustainable action and represent a vital insurance policy against irreversible damage from climate change, whereas failure to acknowledge the relationship between climate change and biodiversity and failure to act swiftly and in an integrated manner could undermine efforts for improvements in both areas.

However, the data points to early intervention (day 7 and day 21) as generally being more effective than later intervention (day 48) in relation to structural degeneration, as changes may have become irreversible by such a late time point.

Mentor of the Year recipient Donahue's research focuses on developing and applying new approaches to identify early changes in tissue function that may precede irreversible damage, and in turn can be used to triage patients for early, personalized therapies.

However, further investigations are needed to clarify whether previous metabolic influences at the level of quiescent satellite cells in vivo can induce irreversible metabolic changes in cultured human myotubes.

«Ocean warming, acidification and deoxygenation are essentially irreversible on centennial time scales,» found the Royal Society, a London - based group specializing in scientific research, in a 2011 paper, «[O] nce these changes have occurred, it will take centuries for the ocean to recover.

Amazon rainforest, West African monsoon and others) could be pushed towards abrupt or irreversible change if warming continues in a business - as - usual way throughout this century.

Knowledge of these thresholds is key to the sustainable management of ecosystems and to anticipating irreversible changes and / or ecological collapse,» wrote Alfredo Huete, a researcher at the University of Sydney in Australia, in an accompanying commentary on the study in Nature.

The principle of proteolysis in vivo is to instigate irreversible changes to a set of protein substrates that alters their function and generates the required biological event.