Sentences with phrase «is a therapeutic agent»
It is also anti-inflammatory in nature and hence is a therapeutic agent for prevention of several diseases associated with inflammation.
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This two - day workshop (February 22 & 23rd) will focus on the dynamic relationship facets of Dr. Landreth's 10 - session CPRT filial therapy training model, designed to train parents to be therapeutic agents in their children's lives.
This two - day workshop will focus on the dynamic relationship facets of training parents to be therapeutic agents in their children's lives.
Not exact matches
The leader of such a group must be highly skilled in order to help the group per se become a therapeutic agent and to minimize the following dangers: (a) Transference distortions.
It has lost this in two different ways: one is through the psychologizing of religion, whereby the church becomes basically a therapeutic agency, and the other through the politicizing of religion, whereby the church becomes an agent of change, a political institution.
A 1971 research report listed 14 references where chile was cited as a therapeutic agent for cancer.
Breastfeeding is contraindicated in infants with classic galactosemia (galactose 1 - phosphate uridyltransferase deficiency) 103; mothers who have active untreated tuberculosis disease or are human T - cell lymphotropic virus type I — or II — positive104, 105; mothers who are receiving diagnostic or therapeutic radioactive isotopes or have had exposure to radioactive materials (for as long as there is radioactivity in the milk) 106 — 108; mothers who are receiving antimetabolites or chemotherapeutic agents or a small number of other medications until they clear the milk109, 110; mothers who are using drugs of abuse («street drugs»); and mothers who have herpes simplex lesions on a breast (infant may feed from other breast if clear of lesions).
We will now determine the potency of this new botulinum toxin and how it may be used as a therapeutic agent» said Dr Andrew Carter.
«The advantage of being able to adjust a set of genes identified as key autism risk factors may explain the strong and long - lasting efficacy of this therapeutic agent for autism.»
Pellecchia said the road to a therapeutic for human trials is still long and includes the iterative design and synthesis of more potent and selective agents.
OMP - 54F28 (FZD8 - Fc) and a sister compound also developed by OncoMed, vantictumab (OMP - 18R5), are two of the first therapeutic agents targeting this key pathway to enter clinical testing.
«We know that 70 - 75 percent of glioblastoma patients undergo surgery for tumor debulking, and we have previously shown that MSCs encapsulated in biocompatible gels can be used as therapeutic agents in a mouse model that mimics this debulking,» he continued.
«These results provide the basis for the potential implementation of 5 - LO - inhibitors as stem cell therapeutic agents for a sustained AML cure, although this must be investigated further in preclinical and clinical studies in humans,» explains Dr. Ruthardt.
«It is possible that perhaps a therapeutic agent targeting BACE1 in humans might have a similar effect,» he says.
Another interesting aspect to the work is that it demonstrates the possibility of adding new machinery to human cells to enable them to make therapeutic agents in response to disease signals.»
Structure - based drug design, in which the physical structure of a targeted protein is used to help identify compounds that will interact with it, has already been used to generate therapeutic agents for a number of infectious and metabolic diseases.
«The misuse of these substances can not be allowed to continue to curtail their use as tools for understanding the neurobiology of human consciousness, self - awareness and their potential as therapeutic agents.»
Scientists are hopeful that ultimately these cells could be transformed in the laboratory to yield specific cell types needed for a particular treatment, or to cross the «blood - brain barrier» by expressing specific therapeutic agents that are released directly into the brain.
«It is our hope that Dr. Yin's research will lead to additional potential therapeutic agents like ZF143 to reactivate mechanisms for the repair and regeneration of damaged heart muscle tissue in humans.»
And each year the games are becoming more popular — not only as a form of entertainment but as a medium for education or even as a therapeutic agent for keeping people's minds sharp.
There is also a lack of effective therapeutic agents for controlling mucus overproduction in otitis media.
They also allow investigators to consider or reconsider therapeutic agents that were previously deemed too toxic to deliver through a systemic route.
Unlike conventional drugs, BNPs can be designed to deliver therapeutic agents specifically to the site of inflammation.
After a successful postdoc at the Ontario Cancer Institute, where he developed a proprietary platform for the discovery of novel cancer therapeutic agents, Bray was asked to join the former Amgen Research Institute in Toronto (now called the Advanced Medical Discovery Institute and no longer part of the parent company) as the head of their quantitative biology group and act as liaison to Amgen Inc. in California.
«Our findings suggest that PRMT5 is a possible prognostic factor and therapeutic target for glioblastoma, and they provide a rationale for developing agents that target PRMT5 in this deadly disease,» says co-corresponding author Robert A. Baiocchi, MD, PhD, associate professor of medicine and a hematologist at the OSUCCC — James who is also collaborating on an Ohio State effort to develop a PMRT5 inhibitor.
«That's a very important point, because many of the current therapeutic agents being used for lupus have significant side effects.
«This latest finding provides a concise and direct synthesis pathway that, due to the structure of the products delivered, will likely be quite valuable for the discovery and development of therapeutic agents,» says Micalizio, whose work focuses on the design of organic chemical reaction methods and strategies to improve medicine and human health.
Jusko says that, among his students, the hottest topics of interest involve biotech — particularly protein therapeutic agents — because many future new drugs will likely be biologicals.
«Exosomes were first described in the mid-1980s, but we only now are beginning to appreciate their potential as therapeutic agents.
Alpha1 - antitrypsin is already a therapeutic agent used for replacement therapy in deficient individuals suffering from respiratory disease.
She said five therapeutic agents have been selected for initial testing.
Inducing therapeutic ketosis solely with the ketogenic diet can be difficult, however, so the USF researchers created novel metabolic agents that induce ketosis without dietary restriction.
In addition, therapeutic agents can be developed and tested using imaging technologies that are directly translatable to the clinic.
It is our hope that the Phase 3 trial will result in the first therapeutic agent for this condition.»
Clinicians are currently worried that breast cancer patients with low or absent BRCA1 may become resistant to therapeutic agents such as Olaparib.
Surprisingly, if TOR's activity is acutely inhibited by treatment with the therapeutic agent Rapamycin, sleep quality improves even in old flies, suggesting that age - related sleep decline is not only preventable, but also reversible.
«Our work and that of our colleagues on stress and CRF have been mechanistically implicated in Alzheimer's disease, but agents that impact CRF signaling have not been carefully tested for therapeutic efficacy or long - term safety in animal models,» said the study's principal investigator and corresponding author Robert Rissman, PhD, assistant professor in the Department of Neurosciences and Biomarker Core Director for the Alzheimer's Disease Cooperative Study (ADCS).
Dr. Dong said the findings have significant implications in the prevention and treatment of type 2 diabetes and could prove to be useful targets for modulation of insulin sensitivity and glucose homeostasis and as a target for therapeutic agents to increase liver function to prevent diabetes.
For the past two decades, scientists have been developing nanoparticles made from a broad range of materials and adding compounds such as cholesterol to help carry these therapeutic agents into cells.
Medical researchers are now testing many therapeutic agents intended to prevent blood supply to tumors.
Gad Berdugo, CEO of EpiVax Oncology, says that such therapeutic vaccines could be used in combination with checkpoint inhibitors or, potentially, as single agents.
«Together, our findings indicate that these molecular regulators, TRIP - Br2 and GATA3, could be viable targets for small drug molecules that could serve as potential therapeutic agents against obesity,» Liew said.
Regardless of age, the main therapeutic classes of AI medications used in the population were cardiovascular agents such as blood pressure medications, central nervous system agents such as sleeping pills, pain medications, and muscle relaxers, metabolic agents such as medications for diabetes and cholesterol, and psychotherapeutic agents such as antidepressants and antipsychotics.»
«New insights into the biology of heart failure are desperately needed to prompt new types of targeted therapeutic agents,» says senior study author James Bradner of the Dana - Farber Cancer Institute and Harvard Medical School.
Multicomponent reactions are protocols that ease the chemical synthesis of new compounds, and are particularly important to gain molecules with biological activity as therapeutic agents against several pathogens.
Knowing that Notch governs vessel permeability makes it a candidate for new drugs to treat cardiovascular diseases as well, and the team is also investigating the TMD as a potential therapeutic agent itself, as cell models that were exposed to leak - inducing inflammation displayed a dramatic reduction in leakage when they were engineered to express the TMD.
The cancer researchers also found that PAK is still active, when cancer cells have already been treated with the current standard therapeutic agent Imatinib.
UTMD uses microscopic, gas - filled bubbles that can be paired with viral therapies, therapeutic genes and proteins, and imaging agents.
In a study to be published online February 2 in Nature Communications, scientists from the Icahn School of Medicine at Mount Sinai describe an extensive analysis of novel grape - derived compounds, dihydrocaffeic acid (DHCA) and malvidin - 3» - O - glucoside (Mal - gluc), which might be developed as therapeutic agents for the treatment of depression.
Skin cells reprogrammed to act like embryonic stem cells — a breakthrough first reported in human cells 2 weeks ago — are already showing promise as a therapeutic agent.