Functional imaging using in vivo confocal microscopy which allows the analysis of vaso - activity phenomena during hypoxia,
of ischaemia reperfusion events, or of homing cells in pathologic processes, such as tumours or inflammatory diseases.
«
Cold ischaemia,» however, has a serious disadvantage: the clamping of the vessels damages the renal vessels, significantly increasing the long - term risk of renal impairment.
Allen NJ, Rossi DJ and Attwell D (2004) Sequential release of GABA by exocytosis and reversed uptake leads to neuronal swelling in
simulated ischaemia of hippocampal slices.
Káradóttir R, Cavelier P, Bergersen LH, Attwell D (2005) NMDA receptors are expressed in oligodendrocytes and activated
in ischaemia Nature, 438 (7071), 1162 - 6 PubMed 16372011
They found that afternoon surgeries resulted in lower levels of
myocardial ischaemia — reperfusion injury — tissue damage that occurs when blood flows again through the repaired portion of the heart — than did morning surgeries.
MSCs guard against neurological damage
following ischaemia partly through blood - brain barrier related protective mechanisms
People die of
ischaemia because the surge of blood flow to the skin — a cooling mechanism — reduces the flow to other organs.
Clare acted for a Claimant who had to have his leg amputated due to the doctors» failure to
diagnose ischaemia (restricted blood flow) and refer him for treatment earlier.
Not only can
limb ischaemia occur, but also, the blood clots may lead to deep vein thrombosis, stroke, pulmonary embolism, and heart attacks.
Until now, «
cold ischaemia» has been used during the removal of renal tumors.
The combination
of ischaemia and heat cytotoxicity can damage the intestinal lining and release gut content into the bloodstream.
Their study focussed on seven vital organs — heart, brain, intestines, kidneys, liver, lungs and pancreas — and five physiological mechanisms triggered by heat: for the medically - minded, these are
ischaemia, heat cytotoxicity, inflammatory response, disseminated intravascular coagulation and rhabdomyolysis.
Eligible participants were identified from administrative databases and had at least one of the following: a history of myocardial infarction, at least 50 % stenosis in ⩾ 1 coronary vessel, evidence of exercise induced
ischaemia, coronary revascularisation or diagnosis of coronary artery disease.