Sentences with word «ischemia»

The data on the prevalence of myocardial ischemia on myocardial perfusion single photon emission computed tomography (MPS) in symptomatic patients with zero CACS and low to intermediate risk probability is lacking and controversial.

Powers is planning expand his study size and is partnering with another CCTS - funded stroke investigator who developed an animal model of ischemia in order to analyze micro-RNA released in brain tissues at the precise area around a blocked blood vessel.

Functional mesenchymal stem cells derived from human induced pluripotent stem cells attenuate limb ischemia in mice.

Protective effects of Shexiang Tongxin Dropping Pill on pituitrin - induced acute myocardial ischemia in rats.

MicroRNA - 93 inhibits inflammatory responses and cell apoptosis after cerebral ischemia reperfusion by targeting interleukin - 1 receptor - associated kinase 4.

Skeletal myoblasts have been considered as possible candidates for treatment of myocardial ischemia as well.

Dexmedetomidine Protects Mouse Brain from Ischemia - Reperfusion Injury via Inhibiting Neuronal Autophagy through Up - Regulating HIF - 1α.

Therefore, the authors suggest that vitamin D3 may be of clinical importance in the restoration of dysfunctional cardiac endothelium after heart attack, capillary endothelium after brain ischemia (stroke), hypovolemia, vasculopathy, diabetes and atherosclerosis.

Dr. Semenza's research interests include the molecular mechanisms of oxygen homeostasis; gene and stem cell therapy for ischemic cardiovascular disease; the role of HIF - 1 in cancer; and protection of the heart against ischemia - reperfusion injury.

Addition of vitamin D to hypothermia and NAC following neonatal hypoxic ischemia improves functional outcomes and preserves brain volume in male rodents, report researchers at the Medical University of South Carolina (MUSC) in the September 1, 2017 issue of Neuropharmacology.

Inflammation with ischemia can result in irreversible interstitial fibrosis.

We then evaluated whether the encapsulation of hPSC - CDH5 + cells in PA - RGDS could enhance long - term cell survival and vascular regenerative effects in a hind - limb ischemia model with laser Doppler perfusion imaging, bioluminescence imaging, real - time reverse transcription - polymerase chain reaction, and histological analysis.

As a result, Hausenloy said the results suggest the procedure may still be beneficial in other medical settings of acute ischemia / reperfusion injury, such as when treating heart attack patients or in organ transplantation.

TIM - 1 attenuates the protection of ischemic preconditioning for ischemia reperfusion injury in liver transplantation.

â $ œWe have found neuroprotective compounds that can limit damage to the brain during ischemia associated with stroke and other brain injuries, but have minimal side effects, â $ says senior author Stephen Traynelis, PhD, professor of pharmacology at Emory University School of Medicine.

The effects of death and post-mortem cold ischemia on human tissue transcriptomes.

When someone has a heart attack due to a blocked artery, the heart is deprived of oxygen (an effect called ischemia) and cells die.

«3D - printed patch helps guide growing blood vessels: Novel methods provides potential treatment for ischemia.»

Intestinal ischemia increases capillary permeability and can lead to mucosal lesions and hypoxia.

As a result, the animals treated with blueberry, spinach, or spirulina were reported to have reduced ischemia / reperfusion - induced apoptosis and cerebral infraction.

But findings of a 10 - year study by the National Institutes of Health — the Womens Ischemia Syndrome Evaluation (WISE) completed in 2006 — appear to unravel the mystery.

In the Mental Stress Ischemia Mechanisms Prognosis study, 678 adults (average age 63) with heart disease delivered a speech while researchers measured their blood pressure and heart rate, took imaging pictures of their hearts and measured the constriction of tiny arteries supplying blood in their fingers.

«Constriction of peripheral vessels can also induce ischemia in the heart indirectly, because the heart has to pump against increased resistance.»

In addition, Andersson and fellow researchers have shown that the consequences of chronic pelvic ischemia on bladder and prostate structure and function can be improved by certain drugs.

If the Apgar score at 5 minutes is 7 or greater, it is unlikely that peripartum hypoxia — ischemia caused neonatal encephalopathy.

Ischemia results when narrowed, hardened or blocked blood vessels starve tissue, often resulting in heart attack, stroke, gangrene and other serious conditions.

Previous efforts to treat ischemia by creating new blood vessels have focused on delivering angiogenic growth factors like vascular endothelial growth factor (VEGF) to ischemic sites.

This paper emerges from the MIPS (Mental Stress Ischemia Prognosis) study, 2011 - 2014.

«Our results are promising because they show that a combination of gene and cell therapy can improve the outcome in the case of critical limb ischemia associated with aging or diabetes,» says Semenza.

The chitosan gel resembles the alginate material used to encapsulate cells by the Taylor lab. Yoon's team was testing efficacy in a hindlimb ischemia model, in which a mouseâ $ ™ s leg is deprived of blood.

Heart and lung disease or peripheral arterial disease (PAD) can lead to chronic wounds because of related ischemia.

This medical malpractice claim was for delayed diagnosis of mesenteric ischemia, causing massive infection, extended hospitalization, and disfiguring scars.

When ischemia — restricted blood flow to the heart — is present, patients may or may not experience symptoms outside of moments of exertion or high stress.

• LimFlow SA, a Paris - based critical limb ischemia solutions maker, raised $ 33.5 million in Series C funding.

The potent effect on acceleration of wound healing is demonstrated in healthy mice but also in two models of diabetes, one model of peripheral ischemia as well as in a model using human skin biopsies.

I don't know how this specific concern became so common, but — completely independently — multiple Ph.D. recipients described to me an imaginary scenario in which they have to explain, presumably to a shocked flight attendant, that while they really wish they could help the elderly gentleman experiencing coronary ischemia, they're actually the kind of doctor who applies for research funding and presents at journal clubs, not the kind who, you know, does stuff.

As the surgical team watched, doubtless horrified, the area of ischemia gradually extended until it involved most of the length of the gut.

Neuroscientists found that spinal blood flow in rats was unexpectedly compromised long after a spinal cord injury (chronically ischemia), and that improving blood flow or simply inhaling more oxygen produces lasting improvements in cord oxygenation and motor functions, such as walking.

A link between ischemia / reperfusion and UPR has been suggested previously, but compelling evidence was absent until the Cell study emerged.