Sentences with phrase «ischemia as»

Low - dose supplemental testosterone treatment in men with chronic stable angina increased exercise time preceding induced myocardial ischemia as defined by ST depression on EKG.80 Testosterone replacement therapy has also been proven to reduce insulin resistance, visceral adiposity, and cardiovascular risk.

Skeletal myoblasts have been considered as possible candidates for treatment of myocardial ischemia as well.

Not exact matches

As a result, the animals treated with blueberry, spinach, or spirulina were reported to have reduced ischemia / reperfusion - induced apoptosis and cerebral infraction.

«Essentially, they showed me that a large number of traffic incidents are caused by medical conditions while driving, specifically cardiovascular events, such as myocardial infraction and myocardial ischemia,» says Najarian, director of data science at the Michigan Center for Integrative Research in Critical Care.

As the surgical team watched, doubtless horrified, the area of ischemia gradually extended until it involved most of the length of the gut.

Neuroscientists found that spinal blood flow in rats was unexpectedly compromised long after a spinal cord injury (chronically ischemia), and that improving blood flow or simply inhaling more oxygen produces lasting improvements in cord oxygenation and motor functions, such as walking.

The primary endpoint was 30 - day net adverse clinical events (NACE), a composite of major adverse cardiac and cerebral events (MACCE; all - cause death, reinfarction, ischemia - driven target vessel revascularization, or stroke) or any bleeding as defined by the Bleeding Academic Research Consortium (BARC) definition.

Ischemia / reperfusion injury underlies health issues such as heart attack, stroke, and numerous other ailments including diseases of the kidney, liver, skeletal muscles, and more.

In vivo results demonstrated the patches with pre-organized structure reflected a marked improvement in reducing the prevalence of ischemia, while the patches with no organization resulted in the «hairball» situation as described by Chen.

Cutting blood supply to a body region — known as ischemia — is usually harmful in animals.

«Based on the results seen with ADRCs in the PRECISE trial, we designed ATHENA to look at these cells as a possible treatment option for people with refractory chronic myocardial ischemia.»

As a result, Hausenloy said the results suggest the procedure may still be beneficial in other medical settings of acute ischemia / reperfusion injury, such as when treating heart attack patients or in organ transplantatioAs a result, Hausenloy said the results suggest the procedure may still be beneficial in other medical settings of acute ischemia / reperfusion injury, such as when treating heart attack patients or in organ transplantatioas when treating heart attack patients or in organ transplantation.

The micro CT scans clarified that when the hind limb of a mouse suffers from ischemia, the inferior gluteal artery expands and functions as a bypass.

The discoveries are also expected to be helpful in treating patients suffering from ischemia, stroke and neurodegenerative disorders such as Alzheimer's disease by protecting cells and tissues from stress damage.

In addition to her expert skill as a clinician, Dr. Frontera also has many research interests including identifying biomarkers and predictors of early brain injury and vasospasm / delayed cerebral ischemia after subarachnoid hemorrhage and their impact on outcome; determining the efficacy of therapeutic strategies and developing guidelines for the management of patients with intracranial hemorrhage; evaluating the cost, length of stay, quality of life, functional and cognitive outcomes in a broader population of intracranial hemorrhage patients; developing guidelines for the integration of palliative care into the intensive care unit setting; and evaluating the relationship of Zika virus infection, Guillain - Barre, and other neurologic disorders.

Current projects are investigating: 1) the expression of inflammatory genes during ischemia and reperfusion of kidneys during urology transplantation and in mouse models; 2) the expression of inflammatory genes and proteins in urine as markers indicating the presence of rejection in renal allografts; and 3) the role of adhesion molecules and chemokines in directing leukocyte infiltration into organ allografts.

In some patients with coronary artery disease, mental stress may precipitate ischemia — a deficiency in blood flow to the heart â $ «a risk factor for adverse events and death independent of other cardiovascular risk factors such as smoking, cholesterol and diabetes.

Changes in gene expression as a response to death, and during subsequent post-mortem ischemia, might be expected to reflect stochastic variation resulting from the enzymatic processes underlying mRNA degradation.

BM - MNCs are another cell population under extensive evaluation in clinical trials for treatment of cardiovascular diseases and for peripheral vascular disease, including critical limb ischemia, as well as for amyotrophic lateral sclerosis (ALS), stroke, obstructive pulmonary disease and more.

Often wounds become chronic as a result of poor blood flow (ischemia), autoimmune dysfunction, degenerative conditions such as lupus or diabetes, radiation burns or even malnutrition.

Because angina can manifest in a number of different ways than just chest pain, it is important not to discount the following forms of angina as additional signs and symptoms of ischemia:

When this occurs, chest pains (called angina) manifest as the primary symptom of ischemia.

Live - cell experiments involving translational research concepts, such as testing for ischemia - reperfusion in cells for research on stroke, involve a tight regulation of oxygenation as measurements are made in real time.

Ambient levels of PM 2 days before submaximal exercise testing were significantly associated with increased ST - segment depression during the test.17 This finding suggests that air pollution exposure conveys a greater susceptibility to myocardial ischemia, as demonstrated in an experimental study of dogs exposed to CAP.175 These results also offer insight regarding the relationship between exposure to PM and the timing of AMI.11 Significant associations were identified between symptom onset and both acute (levels within 2 hours before symptoms) and subacute (previous - day average concentration) exposures to PM2.5.

Chronic inflammation has been noted as the culprit for multiple diseases and conditions such as Alzheimer's disease (AD), Parkinson's disease, multiple sclerosis, epilepsy, cerebral injury, cardiovascular disease, metabolic syndrome, cancer, allergy, asthma, bronchitis, colitis, arthritis, renal ischemia, psoriasis, diabetes, obesity, depression, fatigue (2)

As a result, the animals treated with blueberry, spinach, or spirulina were reported to have reduced ischemia / reperfusion - induced apoptosis and cerebral infraction.

Subjects were participants in the Women's Ischemia Syndrome Evaluation (WISE) who had reported chest pain and were thus suspected to suffer from myocardial ischemia (defined as pathological loss of or reduction in blood flow — ischemia — to a part of the muscular tissue of the heart — myocIschemia Syndrome Evaluation (WISE) who had reported chest pain and were thus suspected to suffer from myocardial ischemia (defined as pathological loss of or reduction in blood flow — ischemia — to a part of the muscular tissue of the heart — myocischemia (defined as pathological loss of or reduction in blood flow — ischemia — to a part of the muscular tissue of the heart — myocischemia — to a part of the muscular tissue of the heart — myocardium).

The main hypothesis includes a stress preconditioning response mechanism, in which it is believed that periods of nutrient deprivation displays a beneficial mild stress that results in molecular adaptive changes in various tissues, which increases the organism's resistance to bigger stressors such as excitotoxic and oxidative injury, including ischemia (33,71).

Endurance athletes frequently report gastrointestinal impairment during competition, which can include dangerous and debilitating conditions such as nausea, bloating, pain, vomiting, abdominal angina, bloody diarrhea, endotoxemia, hemorrhagic gastritis, and ischemic colitis.28, 29 Causes of gut distress are considered multifactorial, with gastrointestinal ischemia being important, along with mechanical position (e.g. runners versus cyclists) and nutrition.

As the stomach begins to turn, a cascade of pathological events begin to occur: compression of the caudal vena cava and portal vein (blood flow to the heart), reduced cardiac output and myocardial ischemia, shock, perfusion to critical organs is reduced and fatality if not corrected quickly.