Board Certified: American College of Veterinary Internal Medicine (A.C.V.I.M., Internal Medicine) Member: American Veterinary Medical Association (A.V.M.A.) Member: Florida Veterinary Medical Association (F.V.M.A.) Member / President: Treasure Coast Veterinary Medical Association (T.C.V.M.A.) The Ohio State University Alumni Association The Ohio State University College of Veterinary Medicine Alumni Association Member: Veterinary Medical Hyperbaric Society Examination Committee Medical Director for Veterinary Hyperbaric Safety (VHS) an RKLyman, LLC company Hyperbaric Oxygen Therapy Consulting Firm Invited speaker to the 2014 ACVIM Forum, presenting «HBOT in Complete Global
Ischemia in Small Animals» Reviewer: Undersea and Hyperbaric Medicine Journal Licensed Foster Parent, St. Lucie County, Florida (Emergency Care) Editorial Perspective Author, Undersea and Hyperbaric Medicine Journal, Jan / Feb 2015
Natural progesterone, but not medroxyprogesterone acetate, enhances the beneficial effect of estrogen on exercise - induced myocardial
ischemia in postmenopausal women.
In line with previous studies12, 13,15,17,20 our analyses show that the investigation of the impact of post-mortem
ischemia in tissue transcriptomes is essential to properly interpret gene expression estimates obtained from post-mortem tissue samples.
Consistent with this finding, EPOR protein levels continued to rise for 72 h after the end of
ischemia in rat retina [64].
Protective effects of Shexiang Tongxin Dropping Pill on pituitrin - induced acute myocardial
ischemia in rats.
Functional mesenchymal stem cells derived from human induced pluripotent stem cells attenuate limb
ischemia in mice.
«Humans risked limb
ischemia in exchange for bipedal walking: A detailed comparison of mouse and human blood vessels with three - dimensional imaging.»
«Constriction of peripheral vessels can also induce
ischemia in the heart indirectly, because the heart has to pump against increased resistance.»
Powers is planning expand his study size and is partnering with another CCTS - funded stroke investigator who developed an animal model of
ischemia in order to analyze micro-RNA released in brain tissues at the precise area around a blocked blood vessel.
In preclinical studies, hypothermia and anti-oxidant treatment with N - acetylcysteine (NAC) are neuroprotective following neonatal hypoxic
ischemia in females, but less so in males.
Not exact matches
• LimFlow SA, a Paris - based critical limb
ischemia solutions maker, raised $ 33.5 million
in Series C funding.
«Essentially, they showed me that a large number of traffic incidents are caused by medical conditions while driving, specifically cardiovascular events, such as myocardial infraction and myocardial
ischemia,» says Najarian, director of data science at the Michigan Center for Integrative Research
in Critical Care.
I don't know how this specific concern became so common, but — completely independently — multiple Ph.D. recipients described to me an imaginary scenario
in which they have to explain, presumably to a shocked flight attendant, that while they really wish they could help the elderly gentleman experiencing coronary
ischemia, they're actually the kind of doctor who applies for research funding and presents at journal clubs, not the kind who, you know, does stuff.
CYP - 13A12 promotes oxidation of polyunsaturated fatty acids into eicosanoids, signaling molecules that can strongly affect inflammatory pain and
ischemia - reperfusion injury responses
in mammals.
Neuroscientists found that spinal blood flow
in rats was unexpectedly compromised long after a spinal cord injury (chronically
ischemia), and that improving blood flow or simply inhaling more oxygen produces lasting improvements
in cord oxygenation and motor functions, such as walking.
«Multi-mechanism approach to treating neonatal hypoxic
ischemia: Vitamin D added to N - acetylcysteine and hypothermia following neonatal hypoxic
ischemia improves functional outcomes, particularly
in males.»
Jenkins and her team plan to build upon these results with preclinical and clinical studies aimed at understanding the injury mechanisms underlying hypoxic
ischemia and how they differ
in males and females.
Addition of vitamin D to hypothermia and NAC following neonatal hypoxic
ischemia improves functional outcomes and preserves brain volume
in male rodents, report researchers at the Medical University of South Carolina (MUSC)
in the September 1, 2017 issue of Neuropharmacology.
About 6 million patients are seen
in EDs annually for chest pain or other symptoms suggestive of myocardial
ischemia (decreased blood flow to the heart).
«We do show that obstructive coronary artery disease and myocardial
ischemia remain the strongest predictors of future cardiovascular events, but for the first time,
in a randomized comparison we demonstrate the ability of CT angiography (CTA) to identify a large group of at - risk patients who would have been missed by functional stress testing,» says Hoffmann, who is director of the MGH Cardiac MR PET CT Program.
Dr. Thurston and her colleagues investigated associations between menopausal symptoms and risk for CVD complications among postmenopausal women participating
in the National Heart, Lung, and Blood Institute Women's
Ischemia Syndrome Evaluation study.
Therefore, the authors suggest that vitamin D3 may be of clinical importance
in the restoration of dysfunctional cardiac endothelium after heart attack, capillary endothelium after brain
ischemia (stroke), hypovolemia, vasculopathy, diabetes and atherosclerosis.
Chen — together with clinical partners C. Keith Ozaki, MD, FACS, a surgeon at Brigham and Women's Hospital who has expertise
in leg
ischemia, and Joseph Woo, MD, the head of cardiothoracic surgery at Stanford University — have developed a patch that fosters the growth of new vessels while avoiding some of the problems of other approaches.
In vivo results demonstrated the patches with pre-organized structure reflected a marked improvement in reducing the prevalence of ischemia, while the patches with no organization resulted in the «hairball» situation as described by Che
In vivo results demonstrated the patches with pre-organized structure reflected a marked improvement
in reducing the prevalence of ischemia, while the patches with no organization resulted in the «hairball» situation as described by Che
in reducing the prevalence of
ischemia, while the patches with no organization resulted
in the «hairball» situation as described by Che
in the «hairball» situation as described by Chen.
Finally, after the successful use of PEG - IONCs
in static MRA, the scientists conducted a more challenging dynamic imaging to see vascular flow patterns of cerebral
ischemia (the cause of stroke)
in dogs and monkeys.
In the Mental Stress Ischemia Mechanisms Prognosis study, 678 adults (average age 63) with heart disease delivered a speech while researchers measured their blood pressure and heart rate, took imaging pictures of their hearts and measured the constriction of tiny arteries supplying blood in their finger
In the Mental Stress
Ischemia Mechanisms Prognosis study, 678 adults (average age 63) with heart disease delivered a speech while researchers measured their blood pressure and heart rate, took imaging pictures of their hearts and measured the constriction of tiny arteries supplying blood
in their finger
in their fingers.
«This research is important because previous studies have shown that a reduction
in blood supply to the heart (
ischemia) during mental stress doubles the risk of heart attack or death from heart disease,» said Viola Vaccarino, M.D., Ph.D., senior author of the study and professor of epidemiology and medicine at Emory University's Rollins School of Public Health
in Atlanta, Georgia.
A total of 3,155 patients presenting with symptoms suggestive of cardiac
ischemia were included
in the analysis.
Cutting blood supply to a body region — known as
ischemia — is usually harmful
in animals.
«Based on the results seen with ADRCs
in the PRECISE trial, we designed ATHENA to look at these cells as a possible treatment option for people with refractory chronic myocardial
ischemia.»
In other words, evolution has increased the human risk for lower limb
ischemia.
As a result, Hausenloy said the results suggest the procedure may still be beneficial
in other medical settings of acute
ischemia / reperfusion injury, such as when treating heart attack patients or
in organ transplantation.
The higher sensitivity of the cerebellum to what we interpret to reflect changes
in vascular reactivity with marijuana abuse is consistent with clinical findings that report strokes associated with marijuana abuse are more frequently localized
in the posterior circulation and
ischemia is most frequently observed
in cerebellum (25, 54 ⇓ — 56).
In the ExMI group, more severe ischemia was linked with a greater decrease in progenitor cell
In the ExMI group, more severe
ischemia was linked with a greater decrease
in progenitor cell
in progenitor cells.
The discoveries are also expected to be helpful
in treating patients suffering from
ischemia, stroke and neurodegenerative disorders such as Alzheimer's disease by protecting cells and tissues from stress damage.
In addition to her expert skill as a clinician, Dr. Frontera also has many research interests including identifying biomarkers and predictors of early brain injury and vasospasm / delayed cerebral ischemia after subarachnoid hemorrhage and their impact on outcome; determining the efficacy of therapeutic strategies and developing guidelines for the management of patients with intracranial hemorrhage; evaluating the cost, length of stay, quality of life, functional and cognitive outcomes in a broader population of intracranial hemorrhage patients; developing guidelines for the integration of palliative care into the intensive care unit setting; and evaluating the relationship of Zika virus infection, Guillain - Barre, and other neurologic disorder
In addition to her expert skill as a clinician, Dr. Frontera also has many research interests including identifying biomarkers and predictors of early brain injury and vasospasm / delayed cerebral
ischemia after subarachnoid hemorrhage and their impact on outcome; determining the efficacy of therapeutic strategies and developing guidelines for the management of patients with intracranial hemorrhage; evaluating the cost, length of stay, quality of life, functional and cognitive outcomes
in a broader population of intracranial hemorrhage patients; developing guidelines for the integration of palliative care into the intensive care unit setting; and evaluating the relationship of Zika virus infection, Guillain - Barre, and other neurologic disorder
in a broader population of intracranial hemorrhage patients; developing guidelines for the integration of palliative care into the intensive care unit setting; and evaluating the relationship of Zika virus infection, Guillain - Barre, and other neurologic disorders.
Electroacupuncture improves cognitive function through Rho GTPases and enhances dendritic spine plasticity
in rats with cerebral
ischemia - reperfusion.
Current projects are investigating: 1) the expression of inflammatory genes during
ischemia and reperfusion of kidneys during urology transplantation and
in mouse models; 2) the expression of inflammatory genes and proteins
in urine as markers indicating the presence of rejection
in renal allografts; and 3) the role of adhesion molecules and chemokines
in directing leukocyte infiltration into organ allografts.
Kidney - specific reconstitution of the A1 adenosine receptor
in A1 adenosine receptor knockout mice reduces renal
ischemia — reperfusion injury.
GCSF and hypoxia inducible factor - 1α (HIF - 1α) have been shown to up - regulate SDF - 1α
in the infarcted area
in a rabbit
ischemia model and promote the migration of CXCR4 expressing cells towards cardiac tissues [47 - 49].
In some patients with coronary artery disease, mental stress may precipitate ischemia — a deficiency in blood flow to the heart â $ «a risk factor for adverse events and death independent of other cardiovascular risk factors such as smoking, cholesterol and diabete
In some patients with coronary artery disease, mental stress may precipitate
ischemia — a deficiency
in blood flow to the heart â $ «a risk factor for adverse events and death independent of other cardiovascular risk factors such as smoking, cholesterol and diabete
in blood flow to the heart â $ «a risk factor for adverse events and death independent of other cardiovascular risk factors such as smoking, cholesterol and diabetes.
The chitosan gel resembles the alginate material used to encapsulate cells by the Taylor lab. Yoon's team was testing efficacy
in a hindlimb
ischemia model,
in which a mouseâ $ ™ s leg is deprived of blood.
Sphingosine kinase 1 protects against renal
ischemia — reperfusion injury
in mice by sphingosine -1-phosphate1 receptor activation.
In addition, Andersson and fellow researchers have shown that the consequences of chronic pelvic
ischemia on bladder and prostate structure and function can be improved by certain drugs.
Ischemia induces nuclear NOX2 expression
in cardiomyocytes and subsequently activates apoptosis.
Characterization of Neuroprotective Effects of Biphalin, an Opioid Receptor Agonist,
in a Model of Focal Brain
Ischemia.
Role of Cyclooxygenase and Derived Reactive Oxygen Species
in ϱ - Kinase - Mediated Impairment of Endothelium - Dependent Vasodilation and Blood Flow after
Ischemia - Reperfusion of the Rat Kidney.
Critical role of interleukin - 17A
in murine intestinal
ischemia - reperfusion injury.
Neuroprotection
in mice by NGP1 - 01 after transient focal brain
ischemia.
Critical role of extracellular heat shock cognate protein 70
in the myocardial inflammatory response and cardiac dysfunction after global
ischemia - reperfusion.