«Paw pad vasculopathy» may be one manifestation of
ischemic dermatopathy in some breeds.
Ischemic dermatopathy is a term used to group multiple vasculopathic syndromes unified by similar clinical and histopathologic characteristics.
Dogs with Generalized vaccine - induced
ischemic dermatopathy (GVIID) & Generalized idiopathic
ischemic dermatopathy (GIID) share similar clinical features and will be grouped in the discussion below.
Prognosis — generalized vaccine - induced
ischemic dermatopathy may gradually diminish in severity over time.
Long - term surveillance to prevent recurrence of pruritic skin diseases or secondary pyoderma and Malassezia dermatitis — surface cytologic examination looking for organism overgrowth should be performed whenever inflammation seems to be exacerbating in
an ischemic dermatopathy.
Clinical features shared by all 5 subgroups of canine
ischemic dermatopathy given above include alopecia with crusting and post-inflammatory, mottled pigmentary change.
a. Breeds — Miniature and Toy Poodle, Shih Tzu, Shetland Sheepdog, Lhasa Apso, Pomeranian, and Yorkshire Terrier may be at increased risk for both types of adult - onset generalized
ischemic dermatopathy.
Generalized demodicosis and generalized dermatophytosis also may resemble
ischemic dermatopathy.
Generalized idiopathic
ischemic dermatopathy (GIID): An adult - onset generalized
ischemic dermatopathy without a correlative history indicating the likelihood of induction by a rabies vaccine reaction.
All of
the ischemic dermatopathies are diagnosed by clinical features and skin biopsy.
Management of
ischemic dermatopathies is challenging.
A temporal association with puppy vaccination and recrudescence with repeat vaccination was seen in some of the dogs, similar to
some ischemic dermatopathies.
The use of corticosteroids for the treatment of
ischemic dermatopathies is controversial.
The epidermal and dermal changes overlying post-rabies vaccination panniculitis are identical to those seen with other
ischemic dermatopathies.
The etiology of
ischemic dermatopathies is not known.
Other syndromes have been reported that share features with cell - poor vasculopathies and
ischemic dermatopathies.