Sentences with phrase «ischemic heart injury»

Mesenchymal stem cell (MSC)- derived exosomes mediate tissue regeneration in a variety of diseases including ischemic heart injury, liver fibrosis, and cerebrovascular disease.

Not exact matches

Some autopsy data shows that infants of smokers have signs of established hypoxic - ischemic cellular injury in the brain and the heart which probably occurred in antenatal life, may have been caused by suboptimal placental function and may have been sub-clinical, but if the baby continues to be in a vulnerable environment exposed to post-natal passive smoking, this could affect autonomic nervous system function and lead to poor temperature control, and poor heart rate and respiration control.

James Mitchell, who studies stress resistance at the Harvard School of Public Health in Boston, was especially interested in ischemic reperfusion injury, a problem that often occurs with heart attacks and strokes, and sometimes even from heart and vascular surgery.

Ischemic heart disease tops the list, followed, in order, by trachea, bronchus and lung cancers; stroke; chronic obstructive pulmonary disease; road injuries; suicide; and diabetes.

Oxygen deprivation followed by reoxygenation causes pathological responses in many disorders, including ischemic stroke, heart attacks, and reperfusion injury.

Ischemic heart disease, stroke, low back and neck pain, road injuries, and COPD have also caused an increasing amount of health loss since 1990.

Earlier studies in STEMI patients showed that ischemic postconditioning improved ST - segment resolution — an important marker of arterial blockage on electrocardiogram — reduced damage to heart muscle, and in some patients limited the extent of reperfusion injury.

Data from 3,904 patients who sustained myocardial injury after non-cardiac surgery suggested that ischemic injury (i.e., an injury caused by a lack of oxygen) to heart tissue after non-cardiac surgery explained 24 percent of deaths in the first 30 days after surgery.

However, the study did reveal a statistically significant 15 percent reduction in heart injury occurring within the first 72 hours after surgery in the remote ischemic preconditioning group as compared to the control.

«This finding suggests remote ischemic preconditioning protected the heart muscle against injury during bypass surgery, though unfortunately this effect was not associated with improved long - term clinical outcomes,» Hausenloy said.

Dr. Semenza's research interests include the molecular mechanisms of oxygen homeostasis; gene and stem cell therapy for ischemic cardiovascular disease; the role of HIF - 1 in cancer; and protection of the heart against ischemia - reperfusion injury.

He studies the processes that regulate blood vessel function and response to injury, with emphasis on the role of lipid - lowering medications in preventing ischemic stroke, coronary artery disease, and heart failure.