Although medical and surgical treatments available today for the
ischemic heart disease patients diminish the risk of acute myocardial infarction and reduce to some extent the incidence of recurrent heart attack, one of the unsolved challenges is to affect
myocardium remodeling occurring during
ischemic heart failure.
More interestingly, the effects on infarction size, survival rates and cardiac function can be observed even if the dietary intervention is induced after the
ischemic event, by increasing the expression of angiogenic factors and increased vascularization of the damaged
myocardium, proposing a novel non-pharmacological therapy for subjects with chronic heart failure (43).