The researchers, who evaluated the BSCB in test animals at seven and 30 days after stroke modeling, found that
ischemic stroke damaged the gray and white matter in the cervical spinal cord on both sides of the spinal column, based on analysis of electron microscope images.
Not exact matches
A team of researchers at the University of South Florida investigating the short and long - term effects of
ischemic stroke in a rodent model has found that
stroke can cause long - term
damage to the blood - spinal cord barrier (BSCB), creating a «toxic environment» in the spinal cord that might leave
stroke survivors susceptible to motor dysfunction and disease pathology.
Dr. Paul R. Sanberg, Distinguished University Professor, a co-author of the paper, concluded that «these novel data showing BSCB
damage in subacute and chronic
ischemic stroke may lead to development of new therapeutic approaches for patients with
ischemic cerebral infarction.»
«This study, carried out using laboratory rats modeling
stroke, demonstrated that
ischemic stroke — in both its subacute and chronic stages —
damages the BSCB in a variety of ways, creating a toxic environment in the spinal cord that can lead to further disability and exacerbate disease pathology,» said study lead author Dr. Svitlana Garbuzova - Davis, associate professor in USF's Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair.
In an ongoing clinical trial funded by the U.S. National Institutes of Health, 3K3A - APC alone is being given to patients within a few hours of
ischemic stroke (blocked blood flow to the brain), to determine if the protein can help protect against brain
damage.
The risk of
stroke dramatically increases in the days following an attack, and the transient
ischemic attack could present a chance to minimize the risk or find a cause in order to prevent the permanent neurologic
damage that results due to a
stroke.
He was later diagnosed as having an
ischemic stroke, which resulted in significant
damage to his brain stem.
A mini-
stroke is also known as a TIA (Transient
Ischemic Attack) and presents the same symptoms as a full
stroke, but the patient doesn't experience any permanent neurological
damage.