«The findings are important because they shed new light on the biological process needed to increase blood flow in
ischemic tissues.»
The study supports the idea that patients with coronary artery disease may benefit from cardiac rehab programs, which drive the progenitor cells into
the ischemic tissue, so they can contribute into vascular repair and regeneration.
«We propose that VEGF and R - Ras activation of Akt signaling are complementary to each other, both are necessary to generate fully functional blood vessels to repair
ischemic tissue,» Dr. Komatsu said.
Not exact matches
Immediate applications for the oxygen - sensing bandage include monitoring patients with a risk of developing
ischemic (restricted blood supply) conditions, postoperative monitoring of skin grafts or flaps, and burn - depth determination as a guide for surgical debridement — the removal of dead or damaged
tissue from the body.
Intravenous thrombolytic therapy with recombinant
tissue plasminogen activator (rtPA) can improve outcomes for patients with
ischemic stroke treated within 4 1/2 hours of the onset of symptoms.
Data from 3,904 patients who sustained myocardial injury after non-cardiac surgery suggested that
ischemic injury (i.e., an injury caused by a lack of oxygen) to heart
tissue after non-cardiac surgery explained 24 percent of deaths in the first 30 days after surgery.
If the compound identified in this study successfully reduces
tissue death and improves recovery in further experiments, it could lead to new approaches for preserving brain cells after an
ischemic stroke,» said Francesca Bosetti, Ph.D., Pharm.D., program director at the NIH's National Institute of Neurological Disorders and Stroke (NINDS).
About seven of every eight strokes are
ischemic: They occur when a blood clot cuts off oxygen flow to one or another part of the brain, destroying
tissue and leaving weakness, paralysis and sensory, cognitive and speech deficits in its wake.
The clot - busting drug
tissue plasminogen activator (tPA) to treat
ischemic stroke, should be given within 4.5 hours of symptom onset.
Previous clinical and animal research showed that mice receive less
tissue damage under
ischemic condition than humans, but the cause of the difference was not clear.
Only protein coding genes with a correlation > = 0.4 with the
tissue ischemic time were used in order to reduce the computational burden of model fitting.
These standards relate to stroke rehabilitation & education, dysphagia screening, assessment of functional communication measures, use of antithrombotic agents, statin drugs, and
tissue plasminogen activator, and management of transient
ischemic attacks and migraine, and other related topics.
Here we analyze the GTEx21, 22,23,24,25 RNA - sequencing data to investigate the impact of death and the post-mortem cold
ischemic interval on the transcriptomes of human
tissues.
Effects of warm
ischemic time on gene expression profiling in colorectal cancer
tissues and normal mucosa.
Okyanos cardiac cell therapy targets the restoration of blood flow to the heart and repairs damaged heart
tissue caused by heart attack or
ischemic and non-
ischemic heart disease.
The treatment of common bile duct (CBD) disorders, such as biliary atresia or
ischemic strictures, is restricted by the lack of biliary
tissue from healthy donors suitable for surgical reconstruction.
The generation of bioengineered biliary
tissue could contribute to the management of some of the most impactful cholangiopathies associated with liver transplantation, such as biliary atresia or
ischemic cholangiopathy.
Mesenchymal stem cell (MSC)- derived exosomes mediate
tissue regeneration in a variety of diseases including
ischemic heart injury, liver fibrosis, and cerebrovascular disease.
However, if the asphyxia persists the baby can develop hypoxic -
ischemic encephalopathy, a type of brain damage that destroys
tissue in the cerebral motor cortex and other areas of the brain.