Sentences with phrase «islet autoimmunity resulted»
«The Pre-POINT pilot study demonstrated that daily oral administration of 67.5 mg of insulin to genetically at - risk healthy children without signs of islet autoimmunity resulted in an immune response without hypoglycemia.
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In a pilot study that included children at high risk for type 1 diabetes, daily high - dose oral insulin, compared with placebo, resulted in an immune response to insulin without hypoglycemia, findings that support the need for a phase 3 trial to determine whether oral insulin can prevent islet autoimmunity and diabetes in high - risk children, according to a study in the April 21 issue of JAMA, a theme issue on child health.