Creation of a rich subcutaneous vascular network with implanted adipose tissue - derived stromal cells and adipose tissue enhances subcutaneous grafting of
islets in diabetic mice.
Not exact matches
In these two microscopy images, human islets (the source of insulin cells) were poisoned with a drug to remove the insulin cells, and then treated with either an empty virus (left panel) or the therapeutic virus (right panel), and then grown in a diabetic mous
In these two microscopy images, human
islets (the source of insulin cells) were poisoned with a drug to remove the insulin cells, and then treated with either an empty virus (left panel) or the therapeutic virus (right panel), and then grown
in a diabetic mous
in a
diabetic mouse.
(A) Isolated
islets from 3 - wk - old, female, Tg - hIAPP
mice were cultured
in presence of different concentrations of
islet extracts (IE) from old Tg - hIAPP
mice, with overt
diabetic pathology and age - matched WT
mice.
As shown
in Fig. 2 A, treatment with 1 %
islet homogenate from
diabetic mice leads to punctated accumulation of thioflavin S (ThS)-- positive amyloid aggregates
in cultured
islets.
Inhibition of dipeptidyl peptidase IV with sitagliptin (MK0431) prolongs
islet graft survival
in streptozotocin - induced
diabetic mice.
Anti-LFA-1 improves pig
islet xenograft function
in diabetic mice when long - term acceptance is induced by CTLA4Ig / anti-CD 40L.