Sentences with phrase «isoforms control»
Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes.
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Carstens hopes that further study of Esrp1 and Esrp2, and in particular the proteins whose splice isoforms they control, will uncover useful clues about how these defects arise and how they might be remedied.
The balance of prickle / spiny - legs isoforms controls the amount of coupling between core and fat PCP systems.
Not exact matches
In the current study, deploying TFPI and an isoform of tenascin C, TNC - FN IIIC, with CA 19 - 9 improved performance discriminating stage I and II disease from healthy or benign disease controls.
Oocytes contain a high concentration of an oocyte - specific isoform of p63 which plays a key role as a quality control factor in causing infertility.
Indeed we found that post-mortem samples have a higher entropy than pre-mortem samples (Fig. 7b), reflecting tighter, more controlled, usage of splicing isoforms in the pre-mortem samples.
His graduate work focused on the molecular mechanisms of DNA replication and protein trafficking in mitochondria, and the translational control of novel mitochondrial protein isoforms.
In 60 801 patients with coronary heart disease and 123 504 controls, OR for myocardial infarction was 0 · 96 (0 · 94 - 0 · 98; p < 0 · 0001) per 1 - SD increment in apolipoprotein (a) protein isoform size in serum due to rs2457564, which was directionally concordant with the OR observed in PROMIS for a similar change.
Methods: In this mendelian randomisation study, we measured lipoprotein (a) concentration and determined apolipoprotein (a) isoform size with a genetic method (kringle IV type 2 [KIV2] repeats in the LPA gene) and a serum - based electrophoretic assay in patients and controls (frequency matched for age and sex) from the Pakistan Risk of Myocardial Infarction Study (PROMIS).