Sentences with phrase «isogenic lines»

Near - isogenic lines for measuring phenotypic effects of DIMBOA - Glc methyltransferase activity in maize

Pairwise tests among six isogenic lines ofDrosophila melanogaster were performed to determine whether there is a genotype - specific interaction in the success of sperm.

Not exact matches

To create cell models for the discovery of disease etiology, progression, and treatment, isogenic cell lines can be created from healthy or sick individuals, then compared (Figure 1).

Also, pESC lines, that carry isogenic genome information from the oocyte donors, can be derived and may represent a potential alternative source of stem cells for basic scientific studies as well as novel therapeutic application.

The 1st and 3rd chromosome of the D. melanogaster stock with wAu were replaced with DrosDel w1118 isogenic chromosomes using a first and third double balancer line.

In order to directly compare these two strains in Drosophila melanogaster, we used Wolbachia - infected lines in a genetically identical DrosDel w1118 isogenic background [39].

These isogenic cell lines can be used not only to understand the cellular consequences of disease mutations, but also to perform high throughput genetic and pharmacological screens to both understand the underlying pathological mechanisms and to develop novel therapeutic agents to prevent or treat such diseases.

This study defines a network of synthetic sick / lethal interactions with a set of query genes in a series of isogenic cancer cell lines.

This study defined about 200 negative genetic interactions in the isogenic cancer cell line background.