Sentences with phrase «isolate single genes»

Solving a puzzle of plant manipulation Rather than try to isolate single genes related to secondary cell wall production, the researchers looked at the function of hundreds of transcription factors working within the root xylem's regulatory network.

Not exact matches

Here's why: In the late 90s, technology emerged enabling researchers to rapidly sequence RNA and DNA — giving them the ability to isolate and record the activity of single genes.

In 1986 my research group at the Rockefeller University and another led by Jeffrey Hall of Brandeis University and Michael Rosbash of the Howard Hughes Medical Institute at Brandeis found that the three mutant flies had three different alterations in a single gene named period, or per, which each of our teams had independently isolated two years earlier.

Because Huntington's is determined by a single gene, Liu was able to easily isolate its effects on the birds.

Using the Single - Cell Automatic Analysis and Isolation System developed in 2013, this group isolated single OSNs responding to specific odorants in a time - lapse single - cell - array cytometric manner and identified the OR gene through single cell polymerase chain reaction Single - Cell Automatic Analysis and Isolation System developed in 2013, this group isolated single OSNs responding to specific odorants in a time - lapse single - cell - array cytometric manner and identified the OR gene through single cell polymerase chain reaction single OSNs responding to specific odorants in a time - lapse single - cell - array cytometric manner and identified the OR gene through single cell polymerase chain reaction single - cell - array cytometric manner and identified the OR gene through single cell polymerase chain reaction single cell polymerase chain reaction (PCR).

Thus µSCALE empties the contents of a single capillary onto a collector plate, where the DNA of the isolated cell can be sequenced and the gene variant responsible for the protein of interest can be identified.

The primary isolate env gene was exchanged into the vector in place of the HXB2 env gene, and used in a single round CAT - based virus infecti

We are using a new technique, called single cell RNA sequencing, to isolate thousands of single neurons from human brain tissue, study all the genes that are expressed in each individual cell, and make cell - to - cell comparisons between normal, early stage and late stage AD.

Finding just a single additional case with a deleterious variant in the same gene and overlapping phenotype may provide sufficient evidence to identify the causative gene, but today, case data sits in isolated databases.

WGS revealed i) the presence of recombination, ii) 67 isolates descended monophyletically from a single source connected to Wave 3 of the Seventh Pandemic, and iii) four clinical isolates lacking the cholera toxin gene.

We sought first to examine gene expression in single ES cells isolated directly from specific zones within colonies, with two objectives.

(A) Expression of 5 stem marker genes in single cells isolated from the edge (E), mid (M) or adjacent center (C) region of HES2 colonies.

To this end, we determined the susceptibility of 38 NAPCR1 isolates to ten antibiotics from seven classes using E-tests or macrodilution tests and examined 31 NAPCR1 whole - genome sequences to identify single nucleotide polymorphisms and genes that could explain the observed resistance phenotypes.

Single cell Q - RTPCR for the genes indicated was carried out on 87 cells isolated from different regions of ES colonies.