Dr. John Gearhart, who led a research team that first identified and
isolated human embryonic stem cells, is named director of the institute.
Thomson will be in Santa Barbara only part - time - he remains a tenured senior faculty member at the University of Wisconsin at Madison where, in 1998, he first
isolated human embryonic stem cells.
Thomson, 48, made headlines in 1998 when he announced that his team had
isolated human embryonic stem cells.
Not exact matches
A recent federal court injunction based on a congressional budget amendment passed years before the first
human embryonic stem cells were
isolated has thrown many of the field's ongoing projects into limbo
Although British researchers had discovered
embryonic stem cells in laboratory animals in 1981, it wasn't until 1998 that a Wisconsin team announced it had
isolated stem cells from
human embryos for the first time.
In the decade since the first
human embryonic stem cells were
isolated, the science surrounding
stem cells has grown dramatically.
Using a technique called COSMIC (Crosslinking of Small Molecules to
Isolate Chromatin), the researchers were able to create polyamides that would bind to DNA in
human embryonic stem cells.
Figure 1: The blastocyst is a hollow sphere made of approximately 150
cells and contains three distinct areas: the trophoblast, which is the surrounding outer layer that contains the trophoblast
stem cells and later becomes the placenta, the blastocoel, which is a fluid - filled cavity within the blastocyst, and the inner
cell mass, also known as the embryoblast, which can become the embryo proper, or fetus, and is where
human embryonic stem cells are
isolated from.
John Gearhart, one of the first scientists to
isolate, in 1998,
human embryonic stem cells, also downplayed the therapeutic value of
human cloning, saying «the more we learn about reprogramming, the more I think IPS will be the one of choice.»
Only a few years later,
embryonic stem cells isolated from
humans, once again by Thomson's group, in 1998 (Thomson et al., 1998).
Wicker, no political naïf, brought out the big rhetorical ammo, reminding the senators that it was Jamie Thomson, the University of Wisconsin scientist who first reported
isolating the
cells in 1998, who said: «If
human embryonic stem cell research does not make you at least a bit uncomfortable, you have not thought about it enough.»
In 1998, a group led by Dr. James Thomson, who holds faculty appointments at the University of Wisconsin and the University of California, Santa Barbara (UCSB),
isolated embryonic stem cell from
humans for the first time.
Even though different
cell types were used as the initial starting materials, and they were made to produce different sets of proteins, both groups identified and
isolated cells nearly identical to
human embryonic stem cells, and did so in the same timeframe.
Mesenchymal
Stem Cells: Around the same time that researchers were figuring out how to isolate embryonic stem cells from humans, yet another large group of stem cells was finally admitted into the stem cell fam
Stem Cells: Around the same time that researchers were figuring out how to isolate embryonic stem cells from humans, yet another large group of stem cells was finally admitted into the stem cell fa
Cells: Around the same time that researchers were figuring out how to
isolate embryonic stem cells from humans, yet another large group of stem cells was finally admitted into the stem cell fam
stem cells from humans, yet another large group of stem cells was finally admitted into the stem cell fa
cells from
humans, yet another large group of
stem cells was finally admitted into the stem cell fam
stem cells was finally admitted into the stem cell fa
cells was finally admitted into the
stem cell fam
stem cell family.
The first type of
human pluripotent
stem cells isolated were «
human embryonic stem cells» (hES
cells).
These
human embryonic stem cells (hESCs) are
isolated from early stage embryos.
Starting with transplants of
human oligodendrocytes in the late 1980s [40], and more recently with populations of
human oligodendrocyte progenitor
cells isolated from the developing or adult CNS, or from
human embryonic stem cells, it has been possible to generate extensive myelination upon transplantation into spinal cord injury or into congenital mouse models of hypomyelination [41]--[48].
When scientists first
isolated and cultured
embryonic stem cells in 1998, they opened discovery into the pathways by which a few microscopic
cells grow into the complex
human body with all of its highly specialized parts.
Coinciding with CIRM's goals, three of the floors planned for renovation will accommodate the collaborative work of top
stem cell researcher and UCSB professor James Thompson, who was the first to
isolate human embryonic cells in 1998; the new Mellichamp and Ruth Garland Chairs of bioengineering and molecular mechanisms, respectively; and the «Deep Sequencing Core,» which will house, among other things, a device that will help develop new genetic approaches to important
cell biology inquiries.