Sentences with phrase «isolated subpopulations»

Let me try again: One of the more compelling arguments for the «punk eek» position that most evolution occurs during relatively short (10K - 100K) periods of speciation, which typically occurs in small, isolated subpopulations, is that the stable species which spawns the new species often co-exists with the new species for a considerable period.

«Researchers discover a potential new therapeutic strategy for pancreatic cancer: Researches have have isolated a subpopulation of cancer - associated fibroblasts, which promote tumour growth.

To our knowledge, this study is the first to identify a pluripotency marker in a heterogeneous population of human dermal fibroblasts, to isolate a subpopulation of cells that have a significantly increased propensity to reprogram to pluripotency and to identify a possible mechanism to explain this differential reprogramming.

Not exact matches

As subpopulations moved into isolated areas, how did they remain isolated over a long enough time for new species - defining traits to arise in nuclear genes and become enriched by natural selection to permit speciation?

Here, we show that a non-adherent, stem - like, and metastatic CSC - enriched subpopulation could be isolated by exposing human metastatic breast cancer cell lines to cycles of chronic hypoxia followed by reoxygenation.

We then isolated and exposed this novel subpopulation to additional cycles of hypoxia / reoxygenation and established a distinct subpopulation of cells from these two breast cancer cell lines.

With the recent success of identifying selective inhibitors targeting CSCs, we believe that the newly isolated cycling hypoxia - selected subpopulation may present a new opportunity for chemical screening and discovery of compounds with selective toxicity for metastatic breast CSCs.

If such subpopulations exist and can be identified and isolated, they provide a method to significantly increase the efficiency of reprogramming, enhancing the feasibility of the potential applications based on this technology [1], and a tool for basic research studies to understand the underlying reprogramming mechanisms.

C. Patterns of expression of selected pluripotency genes in subpopulations isolated as shown in A above.

B. Heat map showing gene expression in the four subpopulations isolated as shown in A above.

This subpopulation of Eschrichtius robustus (Lilljeborg, 1861), called the western gray whale, is probably genetically isolated from the only other extant subpopulation, known as the eastern gray whale (LeDuc et al. 2002); the ranges do not appear to overlap (Blokhin 1996).