Shankaran, M.; King, C.; Lee, J.; Busch, R.; Wolff, M.; Hellerstein, M. K. Discovery of novel hippocampal neurogenic agents by using an in vivo stable
isotope labeling technique.
Not exact matches
Very recently a new
technique called positron emission transverse tomography has been developed that makes it possible to detect from outside the skull the presence of deoxyglucose or other substances
labeled with positron emission radioactive
isotopes.
One common
technique for tracking a drug's fate is to
label its molecular framework with heavier
isotopes of hydrogen (either deuterium or tritium).
Proteins were
labeled with
isotopes — a
technique similar to carbon dating for archaeological finds — and followed as cells underwent heat shock and recovery.
Finally, we have developed new
techniques utilizing surface sensing of translation (SUnSET) and bioorthogonal noncanonical amino acid tagging (BONCAT) coupled with stable
isotope labeling by amino acid in cell culture (SILAC) to selectively isolate and quantify newly synthesized proteins within specific temporal windows.