Sentences with phrase «isotypes of»

ADCC / ADCP - enabling isotypes of a-TIGIT surrogate Ab show potent monotherapy efficacy in murine tumor models that correlates to increased T cell activation and reduced Treg infiltration of tumors.

A polyclonal antibody contains a mixture of several isotypes of immunoglobulin G (e.g., IgG1, IgG2a).

In addition, rabbits only have one isotype of IgG molecules with more disulphide bonds.

A monoclonal antibody contains a single isotype of immunoglobulin.

The reactivity of this monoclonal antibody was not dependent on the V (L) or C (L) isotype of the fibril, but rather seemed to be directed toward a beta - pleated sheet conformational epitope expressed by AL and other amyloid proteins.

Not exact matches

«Linkers are stuck in the nanoparticle membrane and bind to a fixed region of any antibody of the same isotype.

By contrast, the anti-GalC antibodies in the GBS patients were of the isotype IgG.

However, these were all of the antibody isotype M (immunoglobulin M, IgM), the earliest antibody type elicited during an acute immune response.

Use negative controls (unstained and isotype control antibodies) to determine gating of populations.

Primary isolates that were incubated with identical concentrations of FITC - and PE - conjugated isotype standards were used to assess the level of background intensity.

AHERF Neurosciences Grant (G9410 -020-Y01)- Co-PI; «Differential expression and sorting of the neuron - specific class III b - tubulin isotype in human neuronal and neuroendocrine tumor cell lines maintained in an organ culture system».

You will find a wide variety of isotypes, species and conjugates in our website, such as gold, biotin, Dylight and Alexa Fluor ® dyes.

HL - 60 cells were stained with 1 µg / mL ab14715 (blue) or an equal amount of an isotype control antibody (red) and analyzed by flow cytometry.

The secondary antibody must be specific to the isotype class of the primary antibody (e.g., IgG or IgM)

(d) Histogram of membrane - bound Tie2 expression in HUVEC and BP compared to isotype control measured by flow cytometry.

Therefore, to maximize detection of the target, it is best to use a secondary antibody that recognizes all isotypes.

(C) Survival of gp33 - immunized mice with LCMV infection following 30 d rest period compared with control mice with ST2 blockade or isotype control Ab treatment.

They were then washed in FACS buffer I and probed in FACS buffer I containing a 1:500 dilution of r - phycoerythrin - conjugated goat anti-mouse IgG (Caltag Laboratories, Carlsbad, CA) or an appropriate isotype control for 15 min in the dark at 4 °C.

Results : The application of specific optimised conditions induce multiple rounds of memory B cell proliferation equally across Ig isotypes, differentiation of memory B cells to antibody secreting cells, and importantly do not alter the Ig genotype of the stimulated cells.

Inhibition of cell proliferation (B) of MCF7, MCF7 / HER2, or BT474 cells treated for 6 days with F3 - IgG, trastuzumab, or isotype control antibody.

An isotyping ELISA was performed by coating a 96 - well plate with 1.25 ug / mL of the IgG1 Isotype Control Antibody and detecting with Alexa Fluor conjugates specific to mouse IgG1, IgG2a, IgG2b, IgG3, IgM and heavy and light chains (H&L) of IgG.

To assess the ability of F3 - IgG to inhibit the proliferation of HER2 - overexpressing breast carcinoma cells, we measured the proliferation of BT474, MCF7 / HER2 and MCF7 breast cancer cell lines in the presence of trastuzumab, F3 - IgG, or an isotype - matched control antibody.

There are many different immunoglobulin isotypes and without L - aspartic acid many of these compounds can not be synthesised.

Included are representations of artworks and museum exhibits created by artists Oliver Ressler, Sayler / Morris, Dread Scott, Temporary Services, and others, original Isotype graphics drawn from the Museum's lexicon of «capitalisms,» and texts from Lucy Lippard, Lester K. Spence, T.J. Demos, Chantal Mouffe, McKenzie Wark and Kim Stanley Robinson, among others.

But once the isotype batteries are used up they will be disposed of only through authorized agents of the manufacturer.

Guanacaste: shore of the Gulf of Nicoya, sea level, Feb. 1900, A. Tonduz13538 (lectotype, designated here, US [B destroyed]; isotypes, BM, GH, K, NY, US).