Sentences with phrase «issues of uncertainties in»

Model forecasts are verified against model control simulations (perfect model experiments), thus overcoming to some extent issues of uncertainties in the observations and / or model parameterizations.

I once heard John Holdren (President Obama's science advisor) speak on the issue of uncertainty in climate predictions.

I return to the issue of the uncertainties in the last point below.c

A highly multi-disciplinary meeting discussing how scientists from a range of disciplines handle the issue of uncertainty in their area of specialisation: i.e. how uncertainty can be characterised, estimated, predicted and communicated.

Not exact matches

In December of 1953, the first issue hit newsstands, its cover undated since publication of a second issue was such an uncertainty.

Such risks, uncertainties and other factors include, without limitation: (1) the effect of economic conditions in the industries and markets in which United Technologies and Rockwell Collins operate in the U.S. and globally and any changes therein, including financial market conditions, fluctuations in commodity prices, interest rates and foreign currency exchange rates, levels of end market demand in construction and in both the commercial and defense segments of the aerospace industry, levels of air travel, financial condition of commercial airlines, the impact of weather conditions and natural disasters and the financial condition of our customers and suppliers; (2) challenges in the development, production, delivery, support, performance and realization of the anticipated benefits of advanced technologies and new products and services; (3) the scope, nature, impact or timing of acquisition and divestiture or restructuring activity, including the pending acquisition of Rockwell Collins, including among other things integration of acquired businesses into United Technologies» existing businesses and realization of synergies and opportunities for growth and innovation; (4) future timing and levels of indebtedness, including indebtedness expected to be incurred by United Technologies in connection with the pending Rockwell Collins acquisition, and capital spending and research and development spending, including in connection with the pending Rockwell Collins acquisition; (5) future availability of credit and factors that may affect such availability, including credit market conditions and our capital structure; (6) the timing and scope of future repurchases of United Technologies» common stock, which may be suspended at any time due to various factors, including market conditions and the level of other investing activities and uses of cash, including in connection with the proposed acquisition of Rockwell; (7) delays and disruption in delivery of materials and services from suppliers; (8) company and customer - directed cost reduction efforts and restructuring costs and savings and other consequences thereof; (9) new business and investment opportunities; (10) our ability to realize the intended benefits of organizational changes; (11) the anticipated benefits of diversification and balance of operations across product lines, regions and industries; (12) the outcome of legal proceedings, investigations and other contingencies; (13) pension plan assumptions and future contributions; (14) the impact of the negotiation of collective bargaining agreements and labor disputes; (15) the effect of changes in political conditions in the U.S. and other countries in which United Technologies and Rockwell Collins operate, including the effect of changes in U.S. trade policies or the U.K.'s pending withdrawal from the EU, on general market conditions, global trade policies and currency exchange rates in the near term and beyond; (16) the effect of changes in tax (including U.S. tax reform enacted on December 22, 2017, which is commonly referred to as the Tax Cuts and Jobs Act of 2017), environmental, regulatory (including among other things import / export) and other laws and regulations in the U.S. and other countries in which United Technologies and Rockwell Collins operate; (17) the ability of United Technologies and Rockwell Collins to receive the required regulatory approvals (and the risk that such approvals may result in the imposition of conditions that could adversely affect the combined company or the expected benefits of the merger) and to satisfy the other conditions to the closing of the pending acquisition on a timely basis or at all; (18) the occurrence of events that may give rise to a right of one or both of United Technologies or Rockwell Collins to terminate the merger agreement, including in circumstances that might require Rockwell Collins to pay a termination fee of $ 695 million to United Technologies or $ 50 million of expense reimbursement; (19) negative effects of the announcement or the completion of the merger on the market price of United Technologies» and / or Rockwell Collins» common stock and / or on their respective financial performance; (20) risks related to Rockwell Collins and United Technologies being restricted in their operation of their businesses while the merger agreement is in effect; (21) risks relating to the value of the United Technologies» shares to be issued in connection with the pending Rockwell acquisition, significant merger costs and / or unknown liabilities; (22) risks associated with third party contracts containing consent and / or other provisions that may be triggered by the Rockwell merger agreement; (23) risks associated with merger - related litigation or appraisal proceedings; and (24) the ability of United Technologies and Rockwell Collins, or the combined company, to retain and hire key personnel.

Actual results, including with respect to our targets and prospects, could differ materially due to a number of factors, including the risk that we may not obtain sufficient orders to achieve our targeted revenues; price competition in key markets; the risk that we or our channel partners are not able to develop and expand customer bases and accurately anticipate demand from end customers, which can result in increased inventory and reduced orders as we experience wide fluctuations in supply and demand; the risk that our commercial Lighting Products results will continue to suffer if new issues arise regarding issues related to product quality for this business; the risk that we may experience production difficulties that preclude us from shipping sufficient quantities to meet customer orders or that result in higher production costs and lower margins; our ability to lower costs; the risk that our results will suffer if we are unable to balance fluctuations in customer demand and capacity, including bringing on additional capacity on a timely basis to meet customer demand; the risk that longer manufacturing lead times may cause customers to fulfill their orders with a competitor's products instead; the risk that the economic and political uncertainty caused by the proposed tariffs by the United States on Chinese goods, and any corresponding Chinese tariffs in response, may negatively impact demand for our products; product mix; risks associated with the ramp - up of production of our new products, and our entry into new business channels different from those in which we have historically operated; the risk that customers do not maintain their favorable perception of our brand and products, resulting in lower demand for our products; the risk that our products fail to perform or fail to meet customer requirements or expectations, resulting in significant additional costs, including costs associated with warranty returns or the potential recall of our products; ongoing uncertainty in global economic conditions, infrastructure development or customer demand that could negatively affect product demand, collectability of receivables and other related matters as consumers and businesses may defer purchases or payments, or default on payments; risks resulting from the concentration of our business among few customers, including the risk that customers may reduce or cancel orders or fail to honor purchase commitments; the risk that we are not able to enter into acceptable contractual arrangements with the significant customers of the acquired Infineon RF Power business or otherwise not fully realize anticipated benefits of the transaction; the risk that retail customers may alter promotional pricing, increase promotion of a competitor's products over our products or reduce their inventory levels, all of which could negatively affect product demand; the risk that our investments may experience periods of significant stock price volatility causing us to recognize fair value losses on our investment; the risk posed by managing an increasingly complex supply chain that has the ability to supply a sufficient quantity of raw materials, subsystems and finished products with the required specifications and quality; the risk we may be required to record a significant charge to earnings if our goodwill or amortizable assets become impaired; risks relating to confidential information theft or misuse, including through cyber-attacks or cyber intrusion; our ability to complete development and commercialization of products under development, such as our pipeline of Wolfspeed products, improved LED chips, LED components, and LED lighting products risks related to our multi-year warranty periods for LED lighting products; risks associated with acquisitions, divestitures, joint ventures or investments generally; the rapid development of new technology and competing products that may impair demand or render our products obsolete; the potential lack of customer acceptance for our products; risks associated with ongoing litigation; and other factors discussed in our filings with the Securities and Exchange Commission (SEC), including our report on Form 10 - K for the fiscal year ended June 25, 2017, and subsequent reports filed with the SEC.

«The size and volatility in this (is similar to) small cap issues, which speaks to uncertainty,» said Howard Silverblatt of S&P Dow Jones Indices.

Important factors that could cause our actual results and financial condition to differ materially from those indicated in the forward - looking statements include, among others, the following: our ability to successfully and profitably market our products and services; the acceptance of our products and services by patients and healthcare providers; our ability to meet demand for our products and services; the willingness of health insurance companies and other payers to cover Cologuard and adequately reimburse us for our performance of the Cologuard test; the amount and nature of competition from other cancer screening and diagnostic products and services; the effects of the adoption, modification or repeal of any healthcare reform law, rule, order, interpretation or policy; the effects of changes in pricing, coverage and reimbursement for our products and services, including without limitation as a result of the Protecting Access to Medicare Act of 2014; recommendations, guidelines and quality metrics issued by various organizations such as the U.S. Preventive Services Task Force, the American Cancer Society, and the National Committee for Quality Assurance regarding cancer screening or our products and services; our ability to successfully develop new products and services; our success establishing and maintaining collaborative, licensing and supplier arrangements; our ability to maintain regulatory approvals and comply with applicable regulations; and the other risks and uncertainties described in the Risk Factors and in Management's Discussion and Analysis of Financial Condition and Results of Operations sections of our most recently filed Annual Report on Form 10 - K and our subsequently filed Quarterly Reports on Form 10 - Q.

Uncertainty about the economy and fiscal issues are expected to weigh on the franchise sector in 2013, but it is still expected to outpace other industries in terms of growth, according to the report.

To explain why this big gap in valuations isn't a sign of over-valuation, the CAPE's critics cite lots of individual issues in these nations that make them riskier bets than the U.S., such as looming Brexit in the U.K. and Germany's uncertainty regarding future leadership.

On the other hand, commenters supporting the proposed 60 - day delay or a longer or indefinite delay argued that such delay would be appropriate, because it would provide sufficient time for the Department to complete its review of the Rule and PTEs in conformance with the President's Memorandum without issuing a series of extensions that could create market frictions due to uncertainty regarding whether the Department would ultimately leave the Rule in place, revise it, or rescind it.

Given these positive surprises, and because monetary policy must be forward - looking to achieve our inflation target, Governing Council's discussions focused on three main issues: first, the extent to which recent strength is signalling stronger economic momentum in Canada and globally; second, how heightened levels of uncertainty, particularly about US tax and trade policies, should be incorporated in our outlook; and third, how much excess capacity the economy currently has, and the growth rate of potential output going forward.

Of course, there is no shortage of fundamental issues to worry about: another downgrade to the outlook for global growth, uncertainty about the economic transition in China, the pace of normalization in the United States, worries about Europe, worries about Japan, just to cite a feOf course, there is no shortage of fundamental issues to worry about: another downgrade to the outlook for global growth, uncertainty about the economic transition in China, the pace of normalization in the United States, worries about Europe, worries about Japan, just to cite a feof fundamental issues to worry about: another downgrade to the outlook for global growth, uncertainty about the economic transition in China, the pace of normalization in the United States, worries about Europe, worries about Japan, just to cite a feof normalization in the United States, worries about Europe, worries about Japan, just to cite a few.

While the benefits of distributed ledgers have been much discussed, Bain concluded that actual tools using blockchain for international payments and trade finance remain in their early stages as banks remain challenged by scaling the technology, along with uncertainties surrounding digital currencies and privacy issues.

One source of uncertainty and frustration in Canada and Mexico is that the Trump administration has not yet made concrete proposals on the most contentious issues — although these may be coming at the fourth round in Washington.

«Businesses are continuing to hire to meet demand, but issues like access to labour, Brexit negotiations and political uncertainty are creating nervousness,» said Kevin Green, chief executive of the Recruitment & Employment Confederation in a statement upon the release of its survey Wednesday.

Uncertainty about labour market reforms, the adequacy of pension systems and future economic conditions may also be discouraging consumers from spending, especially in Germany where these issues have received much publicity.

High debt - to - GDP (gross domestic product) ratios persisted globally, cracks appeared in corporate credit markets and geopolitical issues created a continued backdrop of uncertainty.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

I am in mt mid 30's and in many ways I have becomes wiser as the years have passed by... but also the realization of uncertainty about a lot of issues.

But despite intellectual challenges, issues in his personal life and emotional swings, Lewis is ultimately remembered for his writings on faith: Even when it meant putting aside momentary feelings of uncertainty: «Faith, in the sense in which I am here using the word, is the art of holding on to things your reason has once accepted, in spite of your changing moods... That is why Faith is such a necessary virtue: unless you teach your moods «where they get off,» you can never be either a sound Christian or even a sound atheist.»

And again, this «victory» wasn't rooted in an honest presentation and discussion of the issues; rather, it was the result of voter uncertainty about what the amendment entailed, how it defined cloning, and fear that, if it didn't pass, Missourians wouldn't have access to future stem - cell cures.

Let's see what happens with this, but with Brazil's financial issues at the moment, it'd be a relief if a buyer was able to save the track and race from uncertainty as it's one of the most popular in F1.

In addition, while the Rebels have the luxury of a long coaching search, they have the pressing issue of the new early signing day rule, which will see talent sign elsewhere as uncertainty swirls around Ole Miss..

Adults often face certain signs of uncertainty about their place in life and in their case the lack of financial stability, personal issues and...

«My reading is that with the uncertainty about the outcome of the election whether it be a hung parliament, whether it be a Tory majority or any of that stuff, people actually tuned in much more to local issues.

The push, which advanced on Monday in Albany with a Senate hearing on the issue, comes as the IDC is facing pressure from the left for their coalition government with Senate Republicans in the new era of uncertainty for liberals under the Donald Trump administration.

Former Attorney General issued a video on behalf of Senate Democrats urging Americans to resist in the time of «fear and uncertainty for so many people.»

However, in view of the current uncertainty, including continued discussions with the Government on a range of other issues, all funding and work on the underground development will be delayed until these matters are concluded and a new timetable has been agreed.

The usual health warnings were issued in the form of statistical uncertainty estimates, but these invitations to prudence were given less attention than they deserved by most consumers of the numbers.

«The government needs to set out in more detail how it will meet its target of at least one - for - one replacement of the sold homes, particularly given issues such as the availability of land, the capacity of the building industry and the uncertainty of income from council home sales.»

Former U.S. Attorney General Loretta Lynch issued a video on behalf of Senate Democrats urging Americans to resist in the time of «fear and uncertainty for so many people.»

The governor's proposal would 1) prohibit state sales tax abatements unless a project is in a specific industry eligible for Excelsior tax credits (think «bureaucracy» and «hurts small business» here...), 2) require additional approvals by the relevant Regional Economic Development Council (REDC) and Empire State Development (think «unnecessary oversight and delays» here...), and 3) shift the abatement of state sales tax to a refund that might be issued sometime down the road (think «uncertainty» and «cashflow» here...).

He also hates uncertainty and chaos, and a public pronouncement — however many details are left in the air — is better than a cycle of chatter and doubt about what the Legislature will look like in 2015, what that might mean for the issues he cares about and how that affects his promises to secure action on them.

In vacating her seat, which she has held since 2005, Arroyo creates uncertainty about who will represent her Bronx district, but also brings to the forefront a larger issue about political representation in New York City: the number of women in the CiIn vacating her seat, which she has held since 2005, Arroyo creates uncertainty about who will represent her Bronx district, but also brings to the forefront a larger issue about political representation in New York City: the number of women in the Ciin New York City: the number of women in the Ciin the City

► In this week's issue of STM, Arthur Levine, senior vice chancellor for the health sciences and dean of the University of Pittsburgh School of Medicine in Pennsylvania, and 18 other U.S. academic medical center leaders wrote that «[u] nstable funding for biomedical research has created a hostile working environment that erodes the time available for investigators to conduct their research, discourages innovative high - risk science, threatens to drive established investigators out of U.S. academic biomedical research, and creates uncertainty for trainees and early - career investigatorIn this week's issue of STM, Arthur Levine, senior vice chancellor for the health sciences and dean of the University of Pittsburgh School of Medicine in Pennsylvania, and 18 other U.S. academic medical center leaders wrote that «[u] nstable funding for biomedical research has created a hostile working environment that erodes the time available for investigators to conduct their research, discourages innovative high - risk science, threatens to drive established investigators out of U.S. academic biomedical research, and creates uncertainty for trainees and early - career investigatorin Pennsylvania, and 18 other U.S. academic medical center leaders wrote that «[u] nstable funding for biomedical research has created a hostile working environment that erodes the time available for investigators to conduct their research, discourages innovative high - risk science, threatens to drive established investigators out of U.S. academic biomedical research, and creates uncertainty for trainees and early - career investigators.

Yet much of the document in fact focused on the debatable desirability of the goals of synthetic biology, and on the need to acknowledge the complexities and uncertainties involved in designing novel living organisms — issues which concern many of those working in synthetic biology and which can and should be the subject of open debate.

«The evolutionary consequences of climate change are one of our greatest areas of uncertainty because empirical data addressing this issue are extraordinarily rare; this study is a tremendous step forward in our understanding of how climate change can influence evolutionary process and ultimately species biodiversity,» said Ryan Kovach, a University of Montana study co-author.

Freedman and her colleagues report in this week's issue of Nature that M100 is 56 million light years away, with an uncertainty of 11 per cent.

In an editorial also published in the July 1 issue of Annals of Internal Medicine, Dr. George Sawaya and Dr. Vanessa Jacoby of the Department of Obstetrics, Gynecology and Reproductive Sciences at the University of California, San Francisco write, «The pelvic examination has held a prominent place in women's health for many decades and has come to be more of a ritual than an evidence - based practice... With the current state of evidence, clinicians who continue to offer the examination should at least be cognizant about the uncertainty of its benefits and its potential to cause harm through false - positive testing and the cascade of events it prompts.&raquIn an editorial also published in the July 1 issue of Annals of Internal Medicine, Dr. George Sawaya and Dr. Vanessa Jacoby of the Department of Obstetrics, Gynecology and Reproductive Sciences at the University of California, San Francisco write, «The pelvic examination has held a prominent place in women's health for many decades and has come to be more of a ritual than an evidence - based practice... With the current state of evidence, clinicians who continue to offer the examination should at least be cognizant about the uncertainty of its benefits and its potential to cause harm through false - positive testing and the cascade of events it prompts.&raquin the July 1 issue of Annals of Internal Medicine, Dr. George Sawaya and Dr. Vanessa Jacoby of the Department of Obstetrics, Gynecology and Reproductive Sciences at the University of California, San Francisco write, «The pelvic examination has held a prominent place in women's health for many decades and has come to be more of a ritual than an evidence - based practice... With the current state of evidence, clinicians who continue to offer the examination should at least be cognizant about the uncertainty of its benefits and its potential to cause harm through false - positive testing and the cascade of events it prompts.&raquin women's health for many decades and has come to be more of a ritual than an evidence - based practice... With the current state of evidence, clinicians who continue to offer the examination should at least be cognizant about the uncertainty of its benefits and its potential to cause harm through false - positive testing and the cascade of events it prompts.»

The next meeting will be at the end of this year and a statement of the potential changes in tropical cyclone activity, together with the degree of uncertainty, will be issued following that meeting.

The debate in the media expresses far less uncertainty in this issue than is customary for this level of scientific inquiry.

The Exeter and Greenpeace research team say there are «many questions and uncertainties» around seabed mining, including legal issues and the difficulties of predicting the scale and extent of impacts in advance, and of monitoring and regulating mining activity once it takes place in the deep sea.

Yet much uncertainty hangs on what are expected to be rancorous negotiations with the European Union, covering issues such as the right of foreign citizens to remain in the United Kingdom and a possible exit bill from Brussels.

In view of the ongoing uncertainty about the integrity of the work reported in this paper, and after discussion with the lead author of the research article, Dr Paolo Macchiarini, we now issue an expression of concern about the paper, while reserving a final decision for when current investigations are completeIn view of the ongoing uncertainty about the integrity of the work reported in this paper, and after discussion with the lead author of the research article, Dr Paolo Macchiarini, we now issue an expression of concern about the paper, while reserving a final decision for when current investigations are completein this paper, and after discussion with the lead author of the research article, Dr Paolo Macchiarini, we now issue an expression of concern about the paper, while reserving a final decision for when current investigations are completed.

Global mean temperatures averaged over land and ocean surfaces, from three different estimates, each of which has been independently adjusted for various homogeneity issues, are consistent within uncertainty estimates over the period 1901 to 2005 and show similar rates of increase in recent decades.

Lewis makes a couple of potentially interesting points, chief of which concern the magnitude and uncertainty in the aerosol forcing I used and the time period over which the calculation is done, and I address these issues here.

[Response: A similar conclusion to the one cited by Gavin above was reached independently by a panel of scientists (of which I was a member) convened to report on these issues by the National Academy of Sciences last year, resulting in the NAS report «Radiative Forcing of Climate Change: Expanding the Concept and Addressing Uncertainties (2005)».

Outstanding issues in our understanding of red giants include uncertainties in the amount of mass lost at the surface before helium ignition and the amount of internal mixing from rotation and other processes.