Sentences with phrase «ivermectin sensitive»

Dipping is a fair alternative for ivermectin in collie breeds and in ivermectin sensitive individuals.

It is much easier to use a heartworm preventative, such as low dose Ivermectin that has been used extremely safely for decades (even in the «Ivermectin sensitive» breeds).

Moxidectin is another microcyclic lactone that could be used tyo treat demodicosis (though probably not in ivermectin sensitive animals).

In MDR1 ivermectin sensitive collies and other herding breeds where treatment with ivermectin is not advisable, dips are sometimes needed to augment daily treatment with oral milbemycin for maximum effect.

«This work was originally started by looking at Ivermectin sensitive collies.

Not exact matches

To better identify ivermectin - sensitive dogs, one report recommends initially dosing ivermectin at 50 µg / kg / day and then incrementally increasing the dose by 50 µg / kg during the first days of treatment until the target dose is achieved.19 Another way to gradually increase the dose of ivermectin is to calculate the target dose and corresponding volume, and then give 25 %, 50 %, and 75 % of the total volume for several days before reaching the therapeutic volume (Table 6).

Dogs homozygous for this mutation (MDR1 - 1 delta) display an ivermectin - sensitive phenotype, developing severe neurotoxicosis after a single dose of ivermectin.22 When ivermectin is deemed necessary for a dog, testing for the MDR1 - 1 delta genotype before its use is available through Washington State University's Veterinary Clinical Pharmacology Laboratory (http://www.vetmed.wsu.edu/vcpl/).

Signs of ivermectin toxicosis can occur in any breed but are most common in ivermectin - sensitive breeds such as collies and other herding breeds.20, 21 Ivermectin sensitivity is derived from a frameshift deletion mutation of the multidrug resistance gene (MDR1; the most recent nomenclature is ABC ±), resulting in a severely truncated, nonfunctional proteiivermectin toxicosis can occur in any breed but are most common in ivermectin - sensitive breeds such as collies and other herding breeds.20, 21 Ivermectin sensitivity is derived from a frameshift deletion mutation of the multidrug resistance gene (MDR1; the most recent nomenclature is ABC ±), resulting in a severely truncated, nonfunctional proteiivermectin - sensitive breeds such as collies and other herding breeds.20, 21 Ivermectin sensitivity is derived from a frameshift deletion mutation of the multidrug resistance gene (MDR1; the most recent nomenclature is ABC ±), resulting in a severely truncated, nonfunctional proteiIvermectin sensitivity is derived from a frameshift deletion mutation of the multidrug resistance gene (MDR1; the most recent nomenclature is ABC ±), resulting in a severely truncated, nonfunctional protein product.

Doramectin — Doramectin, another avermectin, has been used in a study involving 23 dogs that received weekly subcutaneous injections of 600 µg / kg.10, 31 None of the animals showed adverse effects with doramectin; however, this drug should not be used in ivermectin - sensitive breeds of dogs.

The results of this study demonstrated that Collies sensitive to the effects of 120 - mu - g of ivermectin (20x) / kg show similar sensitivity to the effects of milbemycin oxine administered at 10 mg / kg (20x).

Please refer to Health Issues for important information on anti-heartworm drugs containing Ivermectin, such as Heartguard, to which Collies and some Shelties are extremely sensitive.

Certain dogs of the Collie breed are more sensitive to the effects of ivermectin administered at elevated dose levels (more than 16 times the target use level) than dogs of other breeds.

This practice rarely involves ivermectin doses comparable to those in the small animal products, and involves doses that could be toxic to ivermectin - sensitive individuals, and most certainly involves doses that could be toxic if combined with spinosad.

Answer: Corgies are not a breed that is sensitive to ivermectin so Heartgard should be fine for your corgi.

That is particularly true if your dog is sensitive to ivermectin or reacts poorly to amitraz (Mitaban ®) dips.

Dogs sensitive to Ivermectin have an anomaly that allows the drug to pass through the blood brain barrier and right into the central nervous system, causing respiratory distress, seizures, comas and death.

Because Demodex cati lives deeper in the hair follicle, it is sensitive to ivermectin in a way that Demodex gatoi is not.

Some breeds have a faulty gene that means they are sensitive to certain drugs such as ivermectin — type heartwormers (including moxidectin, selamectin and doramectin), loperamide (for diarrhea), acepromazine (for sedation) and butorphanol (for pain relief), as well as some chemotherapeutic drugs.

Some Australian Shepherds and mini Aussies are highly sensitive to Ivermectin, available both as a single worming treatment and in a lower dosage as a heartworm preventive under the brand name Heartguard ®.

Not to be used by collies and some shepherds (dogs that are sensitive to Ivermectin) because of the brain barrier issue.

Studies with ivermectin indicate that certain dogs of the Collie breed are more sensitive to the effects of ivermectin administered at elevated dose levels (more than 16 times the target use level) than dogs of other breeds.

This practice rarely involves ivermectin doses comparable to those in the small animal products, certainly involves doses that could be toxic to ivermectin - sensitive individuals, and most certainly involves doses that could be toxic if combined with spinosad.

Collies and similar breeds of dogs can be more sensitive to the side effects of ivermectin than other breeds.

Dogs with MDR1 gene are especially sensitive to certain medications containing ivermectin, such as Heartgard and Iverhart.

*** Ivermectin should be used with caution in breeds known to be potential carriers of the MDR1 gene, a gene that can make carriers highly sensitive to ivermectinIvermectin should be used with caution in breeds known to be potential carriers of the MDR1 gene, a gene that can make carriers highly sensitive to ivermectinivermectin toxicity.

These breeds can be sensitive to ivermectin in medications.

*** Again, Ivermectin should be used with caution in breeds known to be potential carriers of the MDR1 gene, a gene that can make carriers highly sensitive to ivermectinIvermectin should be used with caution in breeds known to be potential carriers of the MDR1 gene, a gene that can make carriers highly sensitive to ivermectinivermectin toxicity.

Ivermectin sensitivity — first described in 1983 some Collies are uniquely sensitive to ivermectin, which is used for parasite Ivermectin sensitivity — first described in 1983 some Collies are uniquely sensitive to ivermectin, which is used for parasite ivermectin, which is used for parasite treatment.

This will, however, very much depend on the amount consumed and whether or not the dog is sensitive to ivermectin.

Not all individuals of collie heritage are sensitive to ivermectin and a test is now available through Washington State University to determine whether an individual should be able to safely take ivermectin or not.

Some individual dogs are sensitive to ivermectin and can die if subjected to a typical therapeutic dose for demodicosis.

It is a very effective treatment; however, certain breeds of dogs may be sensitive to ivermectin.

ProHeart 6 has been evaluated and found safe in pregnant and lactating females and breeding males, ivermectin - sensitive Collies and puppies ≥ 6 months of age.

McNabs are often ivermectin - sensitive dogs.

Selamectin, part of the macrocyclic lactones group is considered safe in dogs and has low or no adverse effects in Ivermectin — sensitive dogs.

The chief drawback in using ivermectin and other macrocyclic lactones is that a few dogs are highly sensitive to them.

Those dogs are not only more prone to be sensitive to ivermectin; they tend to be sensitive to the entire family of avermectins which includes many of the drugs veterinarians use to treat parasites.

That said, there is an important caveat: Some individual dogs, those with the MDR1 mutation, are sensitive to ivermectin and can die if subjected to a typical therapeutic dose for demodicosis.

SAFETY: Studies with ivermectin indicate that certain dogs of the Collie breed are more sensitive to the effects of ivermectin administered at elevated dose levels (more than 16 times the target use level of 6 mcg / kg) than dogs of other breeds.

In most cases, ivermectin - sensitive dogs are members of the collie - family, Old English Sheepdogs or other herding breeds.

Ivermectin demonstrated no signs of toxicity at 10 times the recommended dose (60 mcg / kg) in sensitive Collies.