Sentences with phrase «junction protein occludin»
These increases were accompanied by disruption of tight junctions and a decrease in expression of the tight junction protein occludin.
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Tight junctions, regulated by a molecule called zonulin, as well as by conformational changes in the proteins occludin and claudin, are dynamic intercellular structures that modulate the trafficking or passage of macromolecules from the intestinal lumen to the submucosa and into systemic circulation (Fasano, 2012).
These tight junctions consist of proteins including claudins, occludins, and E-cadherin, among others.