Sentences with phrase «kahweol also»
On the other hand, the anti-oxidant nature of kahweol also points to its potential anti-inflammatory capabilities.
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The global morphological features (including centrifugal growth of the peripheral vessels - relative to the position of the disc -, avoiding the treated area, with an overall decrease in the vascular density) elicited by kahweol treatment are also in agreement with those previously observed for other anti-angiogenic compounds.
Our results indicate that kahweol inhibits two key inflammatory mediators, COX - 2 and MCP - 1, which are also related with angiogenesis.
We also demonstrate the inhibitory effect of kahweol on the endothelial cell potential to remodel extracellular matrix by targeting two key molecules involved in the process, MMP - 2 and uPA.
We have also investigated kahweol antiinflammatory potential through cyclooxygenase - 2 (COX - 2) and monocyte chemoattractant protein 1 (MCP - 1) modulation.