Sentences with phrase «keeps signaling the cell»

Gαs can convert GTP to GDP, but still keeps signaling the cell to grow and divide.

Not exact matches

Immunotherapy differs from more traditional cancer treatments, such as surgery (cutting malignant cells out of the body), chemotherapy and radiation (poisoning the deadly mutants), and even the newer, more precise molecular drugs that attempt to jam the protein signals that tell tumor cells to keep dividing and conquering.

Previous studies showed that, in depressed patients, lipid rafts sequester a protein involved in cell signaling, called GαS, keeping it from doing its job.

«The problem with plasma cell - free liquid biopsy in particular is that the amount of wild - type [DNA] can be very, very high, and so keeping that really rare signal from being swamped out by the wild - type... is key,» says Dawne Shelton, R&D manager for in vitro diagnostic products at Bio-Rad in Hercules, California.

One factor keeping cells in this immature state is the PTEN gene, which suppresses a signalling pathway involved in cell growth.

Unfortunately, most of the loss is in gray matter, the critically important part of the brain composed of neurons, the cells that transmit the signals that keep us breathing and thinking.

Normal SCN cells in the lab keep cycling in synchrony without regard to temperature pulses, but research from another group showed that they could be «reset» by temperature changes if they could no longer signal to each other.

Multiple sclerosis (MS) is caused by immune cells that activate a cascade of chemicals in the brain, attacking and degrading the insulation that keeps neuronal signals moving.

A third class of glia, known as Schwann cells and oligodendrocytes, form insulating sleeves around neurons to keep their electric signals from diffusing.

They depleted their reserves of these chemicals rapidly each time a new auditory signal came in, and they decreased the amount of space within the cells that housed sac - like structures called vesicles — biological storage tanks where neurotransmitter chemicals are kept.

Hong - Zhong Zhang and colleagues at the University of California at San Francisco deciphered the signaling system between a protein in a resistant staph cell that keeps watch for beta - lactams and a second protein that it tells to turn on the gene for beta - lactamase when the drugs are present.

But T cells typically can not attack tumors because the immunosuppressive microenvironment of tumors keeps APCs from turning these signals on.

In order to keep step with the «quickened» mitochondrial translation, somatic cells activated the mTOR signaling pathway in order to accelerate cytoplasmic translation and balance mitochondrial translation.

This mechanism that keeps tumor cells in a state that encourages metastasis requires constant signaling — meaning constant binding of DDR2 to collagen.

By telling brain cells when they have struck gold, the chemical apparently signals them to keep doing whatever they did that led to success.

Scientists at the Wyss Institute at Harvard University set out to solve the mystery of how blood flow keeps the vessels intact and, to their surprise, discovered a completely new cell signaling pathway that is a promising target for drugs to treat a variety of debilitating conditions.

I've still kept my own lab going focusing on understanding what pluripotent stem cells really are, and the extrinsic signals that govern their self - renewal and differentiation.

They identified signals that white blood cells use to control their behaviour, then one by one disabled those signals — discovering that one particular molecule called ERK5 could be manipulated to encourage white blood cells either to throw out pathogens better or to keep them inside and try to kill them for longer.

Tumors, for example, send growth signals to blood vessel cells to keep them growing and thus secure the blood supply to the tumor.

They believe this is because BMP signaling enhances cell renewal — a cell's ability to replicate — and keeps them in a pluripotent state, able to turn into any type of cell.

The prevailing dogma in cancer research is that TGF - β signaling keep cells from morphing into cancer, says Lopez - Diaz.

Rather than preventing the mice developing more fat cells, keeping the weight off was due to the activation of the signaling pathway stopping the existing fat cells get bigger.

Putting weight on bones sends a signal to certain cells to keep building new bone.

In addition, the chronic elevation of cortisol levels caused by excessive stress negatively affects the receptors for both insulin and leptin, which makes it harder for the body to read the signals of those hormones, thus keeping fat trapped in the cells and making you hungry all the time.

Vata is responsible for all movement - related functions of the body, including the breath and heartbeat, the flow of blood in our blood vessels and food in the gut, the countless nerve signals that keep all of our cells and organs functioning, and the communication between cells and organs.

Simple: When your body needs energy because you're consuming fewer calories than you are burning (an energy deficit), then your body releases hormones and enzymes that signal your fat cells to release your fat reserves instead of keeping them in storage.

Insulin also sends signal to all the fat cells in your body to keep hoarding the fat and to keep looking for more fat.

By keeping insulin levels low, less insulin signaling occurs within cells, which results in healthier and longer - living cells.

Cancer occurs when there is a problem with this signal; the damaged cell keeps growing and multiplying.

It's estimated that nearly 97 percent of cell phone signals never reach a destination and are simply lost, but with this technology some of that can be recaptured and used for keeping cell phone's going without needing to be plugged in.

This kit should include a flashlight, some extra batteries, blankets to keep you warm in case you break down, a brightly colored cloth to tie to your antenna to signal help, sand (or cat litter), a candle, some matches, a shovel, non-perishable foods that have a high calorie count, a cell phone, jumper cables and a first - aid kit.