Sentences with phrase «keratinocyte holoclones»
Like keratinocyte holoclones, cancer cell holoclones have been hypothesized to contain self - renewing stem - like cells although direct evidence supporting this hypothesis is still lacking.
http://cancerres.aacrjournals.org/
This suggestion is also consistent with primary keratinocyte holoclones containing normal stem cells (2 — 4).
S1B) prostate cancer cells were cultured at clonal densities, in ∼ 2 weeks clones resembling keratinocyte holoclones, meroclones, and paraclones could be easily identified.
Recent work reveals that keratinocyte holoclones contain self - renewing stem cells and that the ability to form a holoclone is an intrinsic property of the adult stem cells of the hair follicle (4).
Not exact matches
Primary keratinocytes exhibit three typical clonal morphologies represented by holoclones, meroclones, and paraclones, with holoclones containing self - renewing stem cells, and meroclones and paraclones containing more mature and differentiated cells.
Like keratinocyte clones (2 — 4), prostate cancer cell holoclones consisted of tightly packed, small cells and paraclones of larger and fewer cells, whereas the meroclones were made of cells of intermediate sizes and numbers (Supplementary Fig.