Not exact matches
This understanding of
cancer's evolution has
key implications for treatment, he noted, «In addition to pointing out that we will need to target
driver genes that are mutated early in
cancer, this evolutionary approach provides a method that accurately characterizes which genes are being mutated early and late.
Since the specific inducers of
cancer stem cells, which are
key drivers of metastasis, remain elusive, our current findings are a significant advancement in this area.»
In 2007, he joined Columbia University as a post-doc, where he developed network - based computational approaches aimed at identifying
key drivers of initiation and progression of
cancer, as well as mechanisms of therapeutic response and drug resistance.
The group has used this approach to identify
key drivers of metastatic
cancer progression, and is leveraging this information to develop novel nanoparticles to block the spread of prostate and other
cancers.
Five hundred
cancer patients are getting an in - depth look at their genomes as part of a new clinical study that is revealing some of the
key molecular
drivers of metastatic
cancers.
Amidst a great fanfare of recognition and hope, the rise of Immunotherapy as the
key driver for making a significant impact on the treatment of
cancer has seen oncology become the primary area of concern in the Life Sciences sector.