Sentences with phrase «key cellular processes»

Chung and Khurana used the wealth of data from the yeast alpha - synuclein toxicity model to clue them in on key cellular processes that became perturbed as patient neurons aged in the dish.

Dynamic changes of membrane composition and organization are crucial for key cellular processes.

Researchers at the University of California San Diego School of Medicine, with colleagues in Pennsylvania and China, report that not only are there distinct differences in key cellular processes and molecular signatures between rheumatoid arthritis (RA) and osteoarthritis (OA) but, more surprisingly, there are joint - specific differences in RA.

By systematically illustrating key cellular processes and multilayered circuit - host interactions, it further sheds light on quantitative biology towards a better understanding of complex bacterial physiology.

Dr Christos Gkogkas, a Chancellor's Fellow in the University of Edinburgh's Centre for Discovery Brain Sciences, said: «Our study reveals that altered protein synthesis through eIF4E is a key cellular process in the brain that can go awry in depression.

Not exact matches

This so - called microRNA disrupts the expression of two key cellular genes called TGF - β and SMAD3, in a process known as RNA interference (RNAi).

Counteracting the telomere shrinking process is the enzyme, telomerase, that uniquely holds the key to delaying or even reversing the cellular aging process.

To start the process, both the key regulator Atg1 as well as the «waste» to be discarded are separately brought to the precise location where the waste is packed into cellular «garbage bags.»

NMDA receptors are key players in plasticity, the cellular process of learning and memory.

Yang and co-author Chunru Lin, Ph.D., an assistant professor in the same department, confirmed four sites for phosphorylation, a process that turns protein enzymes off and on, impacting key cellular functions.

The study, published in Nature Communications today, focused on protein kinases, enzymes that are key regulators of cellular processes.

The aims of the CEMC are to define the step-wise molecular and cellular alterations that occur during the process of carcinogenesis; determine how environmental exposures cause key genetic mutations and epigenetic changes that underlie carcinogenesis; and discover the impact of environmental factors on the generation and maintenance of cancer stem cells.

New paper available: RNA sequencing of Stentor cell fragments reveals key processes underlying cellular regeneration

Polarization, which confers asymmetry at molecular, cellular and tissue scales, is a fundamental process establishing key features of biological systems.

The quantitative analysis of molecule interactions in bioimaging is key for understanding the molecular orchestration of cellular processes and is generally achieved through the study of the spatial colocalization between different populations of molecules.

The regulation of the transcriptome is key to cellular processes that underpin cell biology, development and tissue function.

The protein, Argonaute - 2, is a key player in RNA interference, a powerful cellular phenomenon that has important roles in diverse biological processes, including an organism's development.

While much remains to be learned about the details of the processes involved in that decline, it now looks as though chromatin, so important to so many cellular functions, plays a key role.

Stress resistance has not been assessed however and so the biological relevance of this finding is currently unknown.32 Several IER trials (75 - 85 % ER on restricted days) in overweight / obese populations have reported reductions in various markers of oxidative stress 37, 41, which in one study was accompanied by a complementary increase in the anti-oxidant uric acid.37 In a direct comparison of IER (75 % ER for two days / week) and CER, both ER strategies displayed equal efficacy in reducing levels of fast - acting advanced oxidation protein products (AOPP) after six months, which displayed a tendency to occur earlier (i.e. at three months) in the IER group.41 Levels of slow - acting (i.e. long term) AOPP tended to decrease in the IER group and increase in the CER group which the authors proposed may have resulted from IER - induced activation of autophagy, a key homeostatic cellular process in which dysfunctional or unnecessary cellular proteins are degraded and recycled.41 On the other hand, a follow - up study using similar IER / CER protocols demonstrated comparable reductions in AOPP in both groups after three months.48 Summary and Future Research Directions

While folate is a key vitamin in the cellular regeneration processes, these minerals have an important role for the healthy function of the body's cells and for their detoxification, helping them flush out excess water, toxins, and sodium, and help maintain an alkaline environment.

NAD + is present in many key cellular functions, from metabolic processes to circadian rhythm regulation to energy production.

London, England About Blog Exploring the molecular mechanisms that underpin key biological processes, the Biochemical Journal is a leading bioscience journal publishing high - impact scientific research papers and reviews on the latest advances and new mechanistic concepts in the fields of biochemistry, cellular biosciences and molecular biology.